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Printable Handouts
Navigable Slide Index
- Introduction
- Criteria for diagnosis of AILD
- Autoimmune Hepatitis (AIH)
- Spectrum of AIH in 2008
- Differential diagnosis: AIH
- Drugs inducing an AIH-like syndrome
- Diagnosis of Wilson disease Leipzig score
- Steps in management of AIH
- Simplified criteria for diagnosis of AIH
- When to question initiation of AIH treatment
- Screening before IST for AIH
- Indication for AIH treatment
- AIH: response to immunosuppressive therapy
- Treatment regiments for adults
- Standard therapy : AIH
- AIH: preventative measures while on treatment
- Monitoring required during IST for AIH
- AIH: remission following therapy
- Remission following IST withdrawal
- AIH: maintenance therapy with Azathioprine
- Treatment failure
- Primary & secondary sclerosing cholangitis
- Potential pathogenesis: sclerosing cholangitis
- Magnetic Resonance Cholangiography
- Role of ERCP in PSC
- PSC: Presenting Features
- Ulcerative colitis: link to PSC
- PSC with Inflammatory Bowel Disease (IBD)
- Survival IBD vs. IBD+PSC
- Causes of death in 45 patients: PSC
- RCT: Ursodeoxycholic acid - PSC
- Why medical therapy fails in PSC?
- Recurrent AILD after OLT
- Primary Biliary Cirrhosis (PBC)
- PBC- physical presentation
- Typical presentation of PBC in 2009
- Meta analysis: RCT in UDCA for PBC
- Liver transplant
- Longterm survival in early PBC
- Survival in PBC +/- Biochemical response
- Survival according to PHG score
- PBS: natural history
- Treatment response and histological change
- Complications of PBC
- What is the drive and the trigger?
- PBC cases in first degree relatives
- PBC: genome wide analysis
- The genetic web of autoimmunity
- Acknowledgments
Topics Covered
- Diagnosis of Autoimmune Liver Disease (AILD)
- Diagnosis of Autoimmune Hepatitis (AIH)
- Steps in management of AIH
- AIH treatment
- Response to immunosuppressive therapy in AIH
- Monitoring during IST for AIH
- Remission following therapy in AIH
- Presenting features of primary & secondary Sclerosing Cholangitis (PSC)
- Ulcerative colitis: link to PSC
- PSC with Inflammatory Bowel Disease (IBD)
- Causes of death in PSC
- PSC treatment
- Medical therapy failure in PSC
- Typical presentation of Primary Biliary Cirrhosis (PBC)
- Liver transplant in PBC vs. PSC
- Survival in PBC
- Treatment response and histological change in PBC
- Complications of PBC
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Talk Citation
Heathcote, J. (2011, January 30). Immune-mediated liver disease [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 6, 2024, from https://doi.org/10.69645/KUSD9543.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Jenny Heathcote has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.