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1. Introduction
2. Overview - diverticular disease (DD)
3. Definitions - diverticular disease
4. Definitions - taxonomy
5. Spectrum of disease (1)
6. Spectrum of disease (2)
7. The Hinchey classification
8. CT scan - Hinchey IIb
9. Radiologic images - Hinchey IIb and III
10. History of diverticular disease
11. DD: increasing incidence
12. Changing incidence of DD on barium enema
13. Autopsy incidence of DD
14. Age incidence of DD
15. Changing sex ratio of diverticular disease
16. Geography of DD
17. Right-sided diverticular disease
18. Complicated diverticular disease
19. Increasing incidence after 10 years
20. Incidence of perforated colonic DD
21. Increasing incidence even with age adjustment
22. Aetiology (1)
23. Aetiology - attributing fibre deficiency to DD
24. Dietary fibre: epidemiological evidence
25. Dietary fibre: experimental evidence
26. Effect of obesity: cohort studies: BMI > 30
27. Abnormal neuromuscular function
28. Abnormal extracellular matrix
29. Management - outline
30. Management - diagnosis
31. Management - principles of surgery
32. Medical therapy for uncomplicated disease
33. Surgical therapy for uncomplicated disease
34. Management of diverticulitis: Hinchey I/II
35. Hinchey I/II: indications for elective surgery
36. Sigmoid diverticulitis 1991 - 2001
37. Elective surgery: notes
38. Management of diverticulitis: Hinchey III/IV
39. Hinchey III/IV: mortality after acute surgery
40. Surgery for diverticulitis: Hinchey III/IV
41. Avoiding laparotomy and resection in Hinchey III
42. Role of laparoscopy in elective resection
43. Societal impact - DD is common
44. Societal impact - DD is highly morbid
45. Societal impact - DD is an orphan disease
46. Summary
47. Concluding remarks

Topics Covered

• Diverticular disease
• Increasing incidence of asymptomatic and complicated forms
• Aetiology of disease and complications: low fibre, aging and obesity (complications)
• Medical management limited, surgical management complex and hazardous
• Overall, high societal cost but little research investment

Links

Series:

• Gastroenterology and Hepatology

Categories:

• Clinical Practice

Therapeutic Areas:

• Gastroenterology & Nephrology

Talk Citation

Publication History

• Published on January 12, 2011
• Archived on May 30, 2021

Financial Disclosures

• Dr. Charles Knowles has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.