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Printable Handouts
Navigable Slide Index
- Introduction
- Oro-pharyngeal and Esophageal Motility
- Stages of Swallow
- Oro-pharyngeal and Esophageal Disorders
- Fluoroscopy
- Manometry
- High-Resolution Manometry
- Esophageal Pressure Topography
- High-Resolution Manometry and Impedance
- Esophageal Pressure-Impedance Topography
- Esophageal Pressure Topography of the UES
- Upper Esophageal Sphincter Relaxation
- Oro-pharyngeal Motility and Dysphagia
- Functional Elements of a Swallow
- Central Nervous System Control of Swallowing
- Oro-pharyngeal Dysphagia
- Dysphagia - Associated Conditions
- Patterns of Oro-pharyngeal Dysphagia
- UES Obstruction / Cricopharyngeal Bar
- UES Relaxation: Increased Intrabolus Pressure
- UES Relaxation: CP Bar After Dilation
- Esophageal Motility and Dysphagia
- Pressure Topography of Esophageal Motility
- Esophageal Striated Muscles Peristalsis
- Central Control of Esophageal Smooth Muscles
- Esophageal Smooth Muscles Innervation
- Esophageal Smooth Muscles Nerves Gradient
- Nerves Gradient - Augmented Contractions
- Nerves Gradient - Simultaneous Contractions
- Nerves Gradient - Reduced Contractility
- EGJ Anatomy and Pressure Morphology
- HRM EGJ Pressure Morphology
- Sliding and Paraesophageal Hiatus Hernia
- Pressure Topography of Esophageal Motility
- Measuring EGJ Relaxation Pressure
- Classification Scheme (1)
- Absent Peristalsis
- Peristaltic Dysfunction (Hypotensive)
- High-Resolution Manometry
- Peristaltic Weakness
- What Esophageal Manometry Can Do
- Hypertensive Peristalsis
- Spasm
- Clinical Evolution of Achalasia
- Classic Achalasia
- Achalasia with Esophageal Compression
- Spastic Achalasia
- Response Rates of Achalasia Treatments
- Functional Obstruction
- Classification Scheme (2)
- Summary
- Acknowledgements
Topics Covered
- Oro-pharyngeal and oesophageal motility can be adequately evaluated using techniques incorporating high-resolution manometry and fluoroscopy
- Major defects in neuromuscular control and function may lead to malnutrition, respiratory complications and a reduction in quality of life
- Oro-pharyngeal and esophageal motor disorders are classified based on patterns of contractile function
- Treatment of motility disorders are determined by manometric patterns of function
- Update interview: New treatments for esophageal motility disorders
- Update interview: Per Oral Endoscopic-(Esophageal) Myotomy (POEM) and treatment of achalasia
- Update interview: Tailoring treatment for type III achalasia and jackhammer esophagus
- Update interview: Mapping out areas of spasm or hypercontractility
- Update interview: Anatomy is an important modulator of esophageal contractile activity
- Update interview: Obstruction related to a stricture, hernia or post-surgical
- Update interview: This is not a true primary motor abnormality and the obstruction should be addressed first
- Update interview: Esophagogastric junction outflow obstruction (EGJOO) requires complementary testing
- Update interview: Obstruction on esophagram and Functional lumen imaging probe (FLIP)
- Update interview: Gut-brain interplay in dysphagia
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Talk Citation
Pandolfino, J.E. (2020, May 15). Oro-pharyngeal and esophageal motility and dysmotility [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 21, 2024, from https://doi.org/10.69645/TMJM2762.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. John E. Pandolfino, Consultant: Given, Takeda, Crospon - Speaker's Bureau: Given - Grant/Research Support (Principal Investigator): Crospon.
Update Available
The speaker addresses developments since the publication of the original talk. We recommend listening to the associated update as well as the lecture.
- Full lecture Duration: 53:51 min
- Update Interview Duration: 24:50 min
A selection of talks on Gastroenterology & Nephrology
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, my name is
Doctor John E Pandolfino,
I'm an associate professor
at Northwestern University,
and Director of the Esophageal Center
at Northwestern Memorial Hospital.
It is my privilege and honor to provide
you with a talk on oro-pharyngeal and
esophageal motility and dysmotility for
the Henry Stewart Talks series.
0:21
Oro-pharyngeal and esophageal
motility encompass a very delicate
interplay between anatomy and
neuromuscular function.
The primary functional responsibilities
of the oropharynx are to transfer food,
prevent aspiration, and
aid in breathing and speech.
In addition, the primary functional
responsibilities of the esophagus are to
transport food, prevent aspiration and
to prevent reflux.
Although all of these functional
responsibilities are extremely important,
today I will focus primarily on the
transfer of food through the oropharynx
and the transport of food
through the esophagus.
Focusing on these two functional
responsibilities will give us a very nice
overview of oropharyngeal and
esophageal motility and dysmotility.
1:10
As mentioned previously, the function of
swallowing through the oropharynx and
the esophagus is a very complicated
interplay between the neuromuscular
function and anatomy of these
particular anatomic components.
When looking at the stages of a swallow,
it is typically broken up into three
specific components, the oral phase, the
pharyngeal phase and the esophageal phase.
When reviewing the various stages of
a swallow, it is important to realize that
there are many differences between
the oropharyngeal phase of swallowing and
the pharyngeal phase of swallowing,
as well as the esophageal
phase of swallowing.
In terms of the muscle type,
in the oral phase and
the pharyngeal phase it is
predominantly striated muscle.
In contrast, in the esophageal phase,
it is a combination of the striated and
smooth muscle.
In addition, there are many differences
in terms of the nervous system control
of the stages of swallow.
As we can see here, in the oral phase
it is predominated by the cortex and
the medulla, while in the pharyngeal and
the esophageal there's more of a complex
of medulla, and in the esophageal phase of
swallowing specifically, the enteric
nervous system is extremely important.
In terms of volitional control,
in oral it is complete,
in pharyngeal there is some, and
in the esophageal phase it is poor.
In terms of sensation, it is very precise
in the oral phase, it is somewhat
good in the pharyngeal phase, but
extremely poor in the esophageal phase.