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Printable Handouts
Navigable Slide Index
- Introduction
- Contents
- Lymphatic system in the CNS
- Anatomy of meninges: layers
- Anatomy of meninges: spaces
- Glymphatic system
- Discovery of lymphatic vessels in central nervous system
- Dorsal vs. basal meningeal lymphatic vessels (1)
- Dorsal vs. basal meningeal lymphatic vessels (2)
- Basal mLVs become lymphedematous and CSF clearance is delayed with ageing
- Model for structure and unidirectional flow of meningeal lymphatic vessels
- Various models explaining drainage pathways of brain wastes
- Controversy over pathways of CSF drainage
- Nasopharyngeal lymphatic plexus is a hub for CSF drainage
- Visualization of human meningeal lymphatics
- MR imaging of meningeal lymphatics in humans
- Visualizing human meningeal lymphatic vessels
- Meningeal lymphatic drainage circuits in human (3D T1 SPACE DANTE MRI)
- Human meningeal lymphatics to cervical lymph node (3D T2 FLAIR)
- Inversion Recovery ALADDIN (IR-ALADDIN) for MR imaging of meningeal lymphatic flow
- CSF pulsation in the CNS
- Coupled electrophysiological, hemodynamic, and CSF oscillations in human sleep
- CSF pulsation measurement using EPI fMRI
- CSF pulsation in traumatic brain injury (TBI) patients
- CSF pulsation in Parkinson’s disease patients
- Lymphatic system and CSF in the eyes
- Ocular lymphatic/glymphatic system (1)
- Ocular lymphatic/glymphatic system (2)
- CSF in subarachnoid spaces of the optic nerve and the brain (1)
- CSF in subarachnoid spaces of the optic nerve and the brain (2)
- Acknowledgements
- Financial disclosures
Topics Covered
- Initial and collecting lymphatics
- Aquaporin4 channel
- Technical advances and limitations in CNS lymphatic system research
- CSF flow in healthy and disease individuals
- Sleep and CSF circulation in optic nerve
Talk Citation
Park, S. (2026, April 30). The lymphatic system in the CNS and the eye: related MR imaging techniques [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved May 4, 2026, from https://doi.org/10.69645/DICF7231.Export Citation (RIS)
Publication History
- Published on April 30, 2026
Financial Disclosures
- There are no commercial/financial matters to disclose.
The lymphatic system in the CNS and the eye: related MR imaging techniques
Published on April 30, 2026
26 min
A selection of talks on Neuroscience
Transcript
Please wait while the transcript is being prepared...
0:00
I'm Sung-Hong Park from KAIST.
I will present on the
lymphatic systems in
the brain and eye and related
MR imaging techniques.
0:12
Here is an overview of the talk.
I will first introduce
the lymphatic system in
the central nervous
system, followed
by a discussion about how
the lymphatic system has
been studied in humans.
Cerebral spinal fluid, CSF,
plays an important role in
brain waste clearance and
drains through the
lymphatic system.
CSF pulsation in
the brain and related
studies will be reviewed.
Finally, I will introduce
the current understanding of
the lymphatic system and the
CSF dynamics in the eyes.
0:55
Let's talk about the lymphatic
system in the brain.
1:00
To better understand the
lymphatic system in the brain,
I will first discuss the
anatomy of the meninges.
The meninges are
protective layers
surrounding the brain
consisting of three layers.
The dura mater is
the outermost layer
closest to the skull.
The arachnoid mater is
the middle layer, and
the pia mater is
the innermost layer directly
covering the brain tissues.
Among these, the dura mater
is the most significant in
this context because
lymphatic vessels
are found within this layer.
The three layers of
the meninges create