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Navigable Slide Index

1. Introduction
2. 2020 estimations
3. 2025 estimations
4. Feminization of ageing
5. Obesity is a cornerstone of vascular risk
6. Globalization of obesity 2005 to 2015
7. Pathologies related to obesity
8. Top 10 causes of death and dementia /AD (1)
9. Top 10 causes of death and dementia /AD (2)
10. Vascular factors and dementia
11. Risk and protective factors related to AD
12. Natural history of dementia
13. Cognitive function by age
14. Risk factor by age
15. Dementia risk - importance of timing
16. Hypertension
17. Midlife blood pressure is a risk factor for AD
18. Pathologies related to hypertension
19. Blood pressure and dementia over 15 years
20. Dementia and systolic blood pressure
21. Overweight and obesity
22. From obesity to dementia - mechanisms
23. Adipose: a metabolically active tissue
24. Metabolic signals
25. BMI and dementia
26. High waist-to-hip ratio and dementia risk
27. Odds of dementia by body mass index
28. Cholesterol and dementia
29. From high cholesterol to dementia - mechanisms
30. Cholesterol, amyloid and AD (1)
31. Cholesterol, amyloid and AD (2)
32. Cholesterol and dementia - epidemiology
33. Mid-life cholesterol and AD
34. Cholesterol level relation to dementia, AD & VaD
35. Risk of dementia by cholesterol levels
36. Type 2 diabetes
37. Regulation of blood glucose
38. Insulin-degrading enzyme (IDE) Insulysin
39. The Maillard reaction in vivo
40. Advanced glycation endproducts in AD
41. Type 2 diabetes is related to dementia
42. Diabetes is related to Mild Cognitive Impairment
43. High insulin
44. High insulin and Alzheimer's disease
45. High insulin or diabetes and Alzheimer's disease
46. Hypoglycemia and dementia risk
47. Do gene data explain vascular risk in dementia?
48. Susceptibility genes: APOE-epsilon-4
49. APOE and Alzheimer's disease
50. APOE in the brain
51. Odds of dementia by APOE-epsilon-4
52. Susceptibility genes: ACE I/D
53. Renin-Angiotensin System (RAS) (1)
54. Renin-Angiotensin System (RAS) (2)
55. Odds of dementia by ACE II
56. Susceptibility genes: three new loci
57. Vascular factors and underlying brain pathologies
58. Cerebral atrophy is related to vascular risk
59. White matter lesions are related to vascular risk
60. BBB integrity is related to vascular risk
61. Blood pressure and neuritic plaques
62. Blood pressure and neurofibrillary tangles
63. Alzheimer's disease prevention
64. Diet
65. Mediterranean-type diet
66. What is a Mediterranean-type diet?
67. Mediterranean-type diet and physical activity
68. Wine
69. Alcohol intake and dementia over 32 years
70. Resveratrol
71. Resveratrol in the brain
72. Energy restriction
73. Fish and omega-3 fatty acids
74. Omega-3 fatty acids and dementia
75. DHA and EPA
76. Vascular factors - risk and protection
77. Vascular risk & dementia over the life course (1)
78. Vascular risk & dementia over the life course (2)
79. Funding
80. Thank you

Topics Covered

• Obesity is the cornerstone of vascular risk
• Vascular risk is associated with dementia and Alzheimer's Disease (AD)
• Hypertension
• Overweight and obesity
• Cholesterol
• Type 2 diabetes
• Genetics of dementia point to vascular risk
• AD neuropathology is related to vascular risk
• AD Prevention
• Vascular risk is related to dementia over the life course

Links

Series:

• Alzheimer's Disease

Categories:

• Clinical Practice
• Neuroscience

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on August 26, 2010

Financial Disclosures

• Dr. Deborah Gustafson has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.