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Navigable Slide Index

1. Introduction
2. DNA methylation
3. Methylation of CpG islands
4. Analysis of CpG islands methylation
5. CpG islands in the genome
6. Example of un-methylated genes
7. Example of methylated genes
8. DNA methylation and gene relationship
9. Methylation of transcription start sites
10. Methylation motifs
11. What determines methylation state?
12. Describing the process
13. Verification of the algorithm
14. Methylation state at implantation
15. The mechanism of turning off genes
16. Tissue specific methylation
17. De novo methylation events
18. Methylation and gene activity
19. The polycomb mark
20. Abnormal de novo methylation in cancer
21. Morphology of the colon
22. Methylation of proliferative cells
23. What is the trigger for de novo methylation?
24. Methylation as a function of age
25. Conclusion

Topics Covered

• Methylation of CpG islands in the genome
• Un-methylated/methylated genes
• DNA methylation and gene relationship
• Methylation of transcription start sites
• Methylation motifs
• What determines methylation state?
• Methylation predicting algorithm
• Methylation state at implantation
• The mechanism of turning off genes
• Tissue specific methylation
• De novo methylation events
• Methylation and gene activity
• The polycomb mark
• Abnormal methylation in cancer
• Methylation of proliferative cells
• Methylation as a function of age

Links

Series:

• DNA Methylation

Categories:

• Cell Biology
• Genetics & Epigenetics

Talk Citation

Publication History

• Published on July 1, 2010
• Reviewed on July 12, 2020

Financial Disclosures

• Prof. Howard Cedar has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.