Biomedical Basics

Punnett squares and genetic predictions

  • Created by Henry Stewart Talks
Published on January 28, 2026   4 min

A selection of talks on Haematology

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This overview addresses Punit squares and genetic predictions with particular emphasis on the fundamental principles of Punnet squares and how they visualize genetic inheritance for both simple and complex traits. We will explore how genotype and phenotype ratios emerge from monohybrid and dihybrid crosses, illustrating mendelian patterns and the extension to multiple traits. The application of Punit squares in predicting genetic outcomes, including human disorders, will be discussed alongside exceptions caused by real world genetic complexities, like incomplete dominance and sex linked inheritance. Finally, we will highlight the enduring importance of Punit squares in genetics, medicine, and agriculture. Let us begin by revisiting the fundamental concepts underpinning Punnett squares, a key tool for understanding genetic prediction. In sexually reproducing organisms, traits are controlled by genes at specific locations on chromosomes. Genes exist in different forms called alleles, and each individual inherits two alleles per gene, one from each parent. These combinations form the genotype, which, along with environmental influences, determine the phenotype. Punnet squares help visualize allele combinations and predict inheritance patterns in offspring. Imagine crossing two pea plants, one with yellow peas and one with green peas, where yellow is dominant and green is recessive. If each parent is homozygous, one dominant, one recessive, all first generation offspring will be heterozygous and display yellow peas.

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Punnett squares and genetic predictions

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