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Printable Handouts
Navigable Slide Index
- Introduction
- Outline of the talk
- Anatomy of motor pathways: spinal cord
- Anatomy of motor pathways: the subcortex
- Pyramidal tract (corticospinal)
- Motor regions of the cerebral cortex
- Disorders of the motor system: spinal cord
- Disorders of the motor system: motor cortex
- Disorders of the motor system: SMA
- Left hemisphere and praxis
- fMRI: sequential movements vs. rest
- Sequential representations and tool use
- Functional organization - mode of control
- Hierarchical organization
- Cellular analysis of motor pathways
- Directional tuning of single cell in motor cortex
- Neural region and representation
- Population vector (1)
- Population vector (2)
- "Brain decoding": form of mind reading
- Brain decoding for rehabilitation
- Brain machine interface systems (BMI)
- 2-dimensional BMI control
- 3-dimensional BMI control
- BMI research and applications in humans
- BMI - Single cell recording from multiple neurons
- Directional tuning in human cells
- BMI in humans - demonstration videos
- Summary: future challenges
Topics Covered
- Anatomy of the motor pathways
- Disorders of the motor system
- Hemispheric asymmetries in motor control
- Functional organization of the cortical motor system
- Cellular representation of movement
- Applications for motor rehabilitation
- Brain-machine interface systems
Talk Citation
Ivry, R. (2021, April 30). Ready, set, action: cortical control of movement [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 27, 2024, from https://doi.org/10.69645/MIWR8545.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Richard Ivry has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Update Available
The speaker addresses developments since the publication of the original talk. We recommend listening to the associated update as well as the lecture.
- Full lecture Duration: 49:57 min
- Update Interview Duration: 15:27 min
A selection of talks on Neurology
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, my name is Richard Ivry and I'm a professor at the University of California.
In today's lecture, we are going to explore how the brain controls movement.
When we consider our amazing mental capabilities,
we sometimes ignore what are the most fundamental aspects of cognition.
The ability to plan and produce skilled movement.
We talk of muscle memory suggesting that the skill of
the basketball superstar or the concert virtuoso is a function of the body rather than the brain.
Yet one could argue that the ability to produce complex and purposeful movement is the central driving force of brain evolution.
Perception, memory, problem-solving,
even language are designed to improve our ability to act,
our precise visual system allows us to manipulate tools.
Our vast memory stores allow us to
recognize which actions are appropriate for a given context.
And language language gives us a way to talk about
our intentions or interpret the actions of others.
1:03
Let me begin by giving you an overview of today's lecture.
There are four parts to it.
First, we're going to describe the anatomy of the motor system,
talking about the different projections down to the spinal cord that
actually allow the muscles to be activated by events within the central nervous system.
Following this, I'm going to be talking about some of the movement disorders.
That have been observed when people have either strokes
or tumors that affect the cerebral cortex.
We'll then turn to review of what I call the functional architecture of the motor system.
Here we'll be looking at the different regions of
the cerebral cortex that are involved in motor control,
asking how they might make
differential contributions to the control of skilled movements.
As part of this will also be looking at
the activity of individual neurons within the motor system and
how we can make sense of how the activity of
these individual neurons produces complex actions.
Finally, we're going to be describing how scientists are taking
that knowledge and translating it into remarkable new therapies
that can assist individuals who have lost the capacity to produce
movement either because of neural injury or because of muscular degeneration.