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Navigable Slide Index

1. Introduction
2. Genetic association studies (1)
3. Genetic association studies (2)
4. Linkage vs. association (1)
5. Linkage vs. association (2)
6. Common variants for common diseases?
7. Genealogy at causal locus (haploid)
8. What if the causal locus isn't genotyped?
9. LD from shared founder haplotype
10. Strength of LD marker
11. Genetic heterogeneity
12. Genotypes at SNPs in strong LD
13. Quality Control (QC)
14. Hardy-Weinberg equilibrium
15. Principal component analysis (PCA)
16. Single SNP tests of association (general model)
17. Single SNP tests of association (1-df tests)
18. Armitage trend test
19. Logistic regression
20. Quantitative traits: linear regression
21. Bayesian analyses
22. Multiple testing
23. Multipoint SNP analyses
24. Haplotype-based analyses
25. Inferring phase
26. Problems with haplotype analyses
27. Haplotype space
28. Imputation
29. Confounding in genetic association studies
30. Population structure
31. P-P plot vs. GC-adjusted P-P plot
32. Family-based tests of linkage and association
33. Software
34. References

Topics Covered

• Linkage vs. association
• Common variants for common diseases
• Genealogy
• Linkage disequilibrium
• Founder haplotypes
• Genetic heterogeneity
• Hardy Weinberg equilibrium
• Principal component analysis
• Single SNP tests of association for case-control data
• Armitage trend test
• Logistic regression
• Quantitative traits
• Bayesian analyses
• Multiple testing
• Haplotype-based analyses
• Inferring phase
• Problems with haplotype analyses
• Imputation
• Genetic association studies
• Family-based tests of linkage and association
• Software

Links

Series:

• Introduction to Human Genetics

Categories:

• Genetics & Epigenetics
• Methods

Talk Citation

Publication History

• Published on December 28, 2009

Financial Disclosures

• Prof. David Balding has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.