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24. Bariatric / obesity surgery- Prof. Henry Buchwald
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26. Adipose-immune interactions in obesity- Dr. Vishwa Dixit
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42 min
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Printable Handouts
Navigable Slide Index
- Introduction
- Adipose-immune interactions
- Paracrine adipocyte-immune cell interactions (1)
- Adipoimmunology
- The adipose organ in obesity
- The immune system
- Adipose tissue macrophages and inflammation
- Differentiation of macrophages
- The macrophages are highly diverged
- Effect of obesity on adipose tissue macrophages
- Macrophages cause insulin resistance in obesity
- ATM polarization model
- Macrophages induced insulin resistance in obesity
- Future directions: ATM and adipose tissue
- Adipose tissue lymphocytes and inflammation
- T-lymphocytes subsets
- CD3+ T cells are present in the adipose tissue
- CD3+ T cells infiltrate within the adipose tissue
- Adipose immune interactions - summary
- Paracrine adipocyte-immune cell interactions (2)
- Age related increased bone-marrow adipocity
- Age related thymic adipocity
- T cells develop in the thymus
- T cell development
- The effect of thymic involution
- Current concepts on causes of thymic involution
- Origin of thymic fat cells (1)
- Origin of thymic fat cells (2)
- Lineage of thymic adipocytes
- Loss of ghrelin signaling and thymic adiposity
- Loss of ghrelin signaling - reduction in naive T cells
- Thymic adipocytes - summary
- Adipose secretory products and immune cells (1)
- Adipose secretory products and immune cells (2)
- Effect of obesity on immune function
- Obesity induced by monogenic leptin deficiency
- Dietary obesity and immune-surveillance
- Dietary obesity reduces lymphoid cellularity
- Dietary obesity induces apoptosis of T cells
- Influenza infection and diet-induced obese mice
- Implications
- Summary
Topics Covered
- Adipoimmunology
- The adipose organ in obesity
- The immune system
- Adipose tissue macrophages and inflammation
- Differentiation of macrophages
- Effect of obesity on adipose tissue macrophages
- Macrophages cause insulin resistance in obesity
- ATM polarization model
- Future directions: ATM and adipose tissue
- Adipose tissue lymphocytes and inflammation
- T-lymphocytes subsets
- CD3+ T cells are present in the adipose tissue
- Age related increased bone-marrow adipocity
- Age related thymic adipocity
- T cells develop in the thymus
- The effect of thymic involution
- Lineage of thymic adipocytes
- Loss of ghrelin signaling and thymic adiposity
- reduction in naive T cells
- Adipose secretory products and immune cells
- Effect of obesity on immune function
- Obesity induced by monogenic leptin deficiency
- Dietary obesity reduces lymphoid cellularity
- Dietary obesity induces apoptosis of T cells
- Influenza infection and diet-induced obese mice
Links
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Talk Citation
Dixit, V. (2009, May 7). Adipose-immune interactions in obesity [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 31, 2025, from https://doi.org/10.69645/DWDQ6352.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Vishwa Dixit has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
