• Epidemiology
• 37 min
  1. Assessment of obesity and classification of patients: historical perspectives and current practice

  • Prof. George Bray
• 40 min
  2. Epidemiology of obesity

  • Prof. Jacob Seidell
• Etiology and Causes
• 59 min
  3. Metabolic, adipose tissue and muscle predictors of obesity

  • Prof. Ian Macdonald
• 41 min
  4. Neural control of food intake and energy balance

  • Prof. Hans-Rudolf Berthoud
• 64 min
  5. Understanding obesity: genes and environment in the determination of body weight

  • Prof. Rudy Leibel
• 47 min
  6. Dietary determinants of obesity

  • Prof. Arne Astrup
• 42 min
  7. Physical inactivity as a determinant of obesity

  • Prof. Wim Saris
• 42 min
  8. Environmental causes of obesity: sociocultural, built environment and economic factors

  • Prof. Shiriki Kumanyika
• 29 min
  9. The developmental origins of obesity

  • Prof. David Barker
• Consequences of Obesity
• 46 min
  10. Obesity, dyslipoproteinemia and inflammation

  • Prof. Robert Eckel
• 23 min
  11. Pathophysiology and management of obesity related hypertension

  • Prof. Arya Sharma
• 22 min
  12. Disorders of overeating

  • Prof. Albert Stunkard
• 20 min
  13. Obesity, weight loss and health-related quality of life

  • Prof. Aila Rissanen
  • Dr. Jarmo Kaukua
• Treatment Options
• 44 min
  14. Lifestyle modification for weight control

  • Prof. Thomas Wadden
• 34 min
  15. Bariatric / obesity surgery

  • Prof. Henry Buchwald
• 48 min
  16. Can obesity be prevented in the current obesogenic environment?

  • Prof. Boyd Swinburn
• 28 min
  17. Pharmacotherapy for obesity: why it is needed

  • Prof. Joe Proietto
• 35 min
  18. Pharmacotherapy for obesity: hunger suppressors

  • Prof. Joe Proietto
• Latest Developments in the Field
• 60 min
  19. Body composition

  • Dr. Steven Heymsfield
• 56 min
  20. Adipose tissue metabolism and obesity

  • Dr. Max Lafontan
• 25 min
  21. Obesity, present and future therapies

  • Prof. Sir Stephen Bloom
• 42 min
  22. Energy expenditure in the lean and obese

  • Prof. Dale Schoeller
• 33 min
  23. Obesity and adiponectin

  • Prof. Philipp Scherer
• 44 min
  24. Ectopic fat: causes, consequences and treatment

  • Prof. Steven Smith
• 47 min
  25. Adipose-immune interactions in obesity

  • Dr. Vishwa Dixit
• 39 min
  26. Health benefits of intentional weight loss

  • Prof. Xavier Pi-Sunyer
• 39 min
  27. Childhood obesity: implications for current and future health

  • Prof. Peter T. Katzmarzyk
• 46 min
  28. The clinical assessment and management of child and adolescent obesity

  • Prof. Louise Baur
• Archived Lectures - These lectures may not cover the latest advances in the field
• 41 min
  29. Gastrointestinal peptides and food intake regulation

  • Prof. Sir Stephen Bloom
• 48 min
  30. Obesity and mortality: questions and controversy

  • Prof. David Allison
• 37 min
  31. Obesity, diabetes and the cluster of the metabolic syndrome

  • Prof. Peter Wilson
• 44 min
  32. New standards in weight management: recent and future drugs for the treatment of obesity

  • Prof. Luc Van Gaal
• 46 min
  33. Health economics of obesity: new insights

  • Dr. Anne Wolf
• 34 min
  34. Bariatric surgery: techniques and mechanisms of action

  • Prof. Walter Pories
• 39 min
  35. Childhood obesity: implications for future health

  • Prof. Peter T. Katzmarzyk
• 14 min
  36. Pharmacotherapy for obesity 1 - the need for pharmacotherapy in weight management

  • Prof. Joe Proietto
• 46 min
  37. Pharmacotherapy for obesity 2 - pharmacological agents in current use & under development

  • Prof. Joe Proietto

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Adipose-immune interactions
3. Paracrine adipocyte-immune cell interactions (1)
4. Adipoimmunology
5. The adipose organ in obesity
6. The immune system
7. Adipose tissue macrophages and inflammation
8. Differentiation of macrophages
9. The macrophages are highly diverged
10. Effect of obesity on adipose tissue macrophages
11. Macrophages cause insulin resistance in obesity
12. ATM polarization model
13. Macrophages induced insulin resistance in obesity
14. Future directions: ATM and adipose tissue
15. Adipose tissue lymphocytes and inflammation
16. T-lymphocytes subsets
17. CD3+ T cells are present in the adipose tissue
18. CD3+ T cells infiltrate within the adipose tissue
19. Adipose immune interactions - summary
20. Paracrine adipocyte-immune cell interactions (2)
21. Age related increased bone-marrow adipocity
22. Age related thymic adipocity
23. T cells develop in the thymus
24. T cell development
25. The effect of thymic involution
26. Current concepts on causes of thymic involution
27. Origin of thymic fat cells (1)
28. Origin of thymic fat cells (2)
29. Lineage of thymic adipocytes
30. Loss of ghrelin signaling and thymic adiposity
31. Loss of ghrelin signaling - reduction in naive T cells
32. Thymic adipocytes - summary
33. Adipose secretory products and immune cells (1)
34. Adipose secretory products and immune cells (2)
35. Effect of obesity on immune function
36. Obesity induced by monogenic leptin deficiency
37. Dietary obesity and immune-surveillance
38. Dietary obesity reduces lymphoid cellularity
39. Dietary obesity induces apoptosis of T cells
40. Influenza infection and diet-induced obese mice
41. Implications
42. Summary

Topics Covered

• Adipoimmunology
• The adipose organ in obesity
• The immune system
• Adipose tissue macrophages and inflammation
• Differentiation of macrophages
• Effect of obesity on adipose tissue macrophages
• Macrophages cause insulin resistance in obesity
• ATM polarization model
• Future directions: ATM and adipose tissue
• Adipose tissue lymphocytes and inflammation
• T-lymphocytes subsets
• CD3+ T cells are present in the adipose tissue
• Age related increased bone-marrow adipocity
• Age related thymic adipocity
• T cells develop in the thymus
• The effect of thymic involution
• Lineage of thymic adipocytes
• Loss of ghrelin signaling and thymic adiposity
• reduction in naive T cells
• Adipose secretory products and immune cells
• Effect of obesity on immune function
• Obesity induced by monogenic leptin deficiency
• Dietary obesity reduces lymphoid cellularity
• Dietary obesity induces apoptosis of T cells
• Influenza infection and diet-induced obese mice

Links

Series:

• Obesity

Categories:

• Clinical Practice
• Immunology
• Metabolism & Nutrition

Therapeutic Areas:

• Cardiovascular & Metabolic
• Immunology & Inflammation

Talk Citation

Publication History

• Published on May 7, 2009

Financial Disclosures

• Dr. Vishwa Dixit has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.