- Co-ordination of G1 Progression
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37 min
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33 min
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35 min
- Chromosome Duplication
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47 min
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51 min
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48 min
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35 min
- Preparing for Mitosis
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27 min
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50 min
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33 min
- Spindle Assembly and Chromosome Segregation
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30 min
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54 min
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43 min
- Mitotic Exit and Cytokinesis
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39 min
- Checkpoints Governing Cell Cycle Progression
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34 min
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54 min
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27 min
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43 min
- The Cell Cycle in Development and Cancer
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62 min
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18 min
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40 min
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30 min
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48 min
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47 min
- Meiosis: A Specialized Cell Cycle
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58 min
- Archived Lectures *These may not cover the latest advances in the field
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24 min
Topics Covered
- Control of cell proliferation
- The budding yeast: Saccharomyces cerevisiae
- Why yeast?
- The budding yeast life cycle
- Placement of START in the cell cycle
- Observing START
- The G1 Checkpoint
- Genetic characterization of START
- Interdependency of Cdk1 with other regulators of START
- Cyclin-Dependent Protein Kinase (CDK)
- The cyclin/CDK cycle
- G1 cyclin/CDK is essential for START
- The role of CDK in START
- Cell cycle dependent expression of Far1 and cyclins
- Periodic accumulation of yeast cell cycle regulators
- The molecular correlate of START
- G1-specific transcription
- G1-specific gene expression and human cancer
- The molecular determinant of START
- Physiological regulators of START
- Mating generates diploid cells from two haploid cells
- Cells of opposite mating types can conjugate
- Stimulation of the mating pheromone cascade elicits three primary responses
- Mating pheromone signaling pathway
- Mating pheromone promotes G1 phase arrest by activating the Cln/CDK inhibitor, Far1
- Regulation of START by other stimuli
- Control of START by cell size
- The molecular basis for the sizer and timer
- What is the signal for achievement of minimum cell size?
Links
Series:
Categories:
Talk Citation
Wittenberg, C. (2009, April 30). START control in yeast [Video file]. In
The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved February 8, 2023, from
https://hstalks.com/bs/1253/.
Publication History
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Published on April 30, 2009
Financial Disclosures
- Prof. Curt Wittenberg has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.