Registration for a live webinar on 'Neuroleptic malignant syndrome' is now open.
See webinar detailsWe noted you are experiencing viewing problems
-
Check with your IT department that JWPlatform, JWPlayer and Amazon AWS & CloudFront are not being blocked by your network. The relevant domains are *.jwplatform.com, *.jwpsrv.com, *.jwpcdn.com, jwpltx.com, jwpsrv.a.ssl.fastly.net, *.amazonaws.com and *.cloudfront.net. The relevant ports are 80 and 443.
-
Check the following talk links to see which ones work correctly:
Auto Mode
HTTP Progressive Download Send us your results from the above test links at access@hstalks.com and we will contact you with further advice on troubleshooting your viewing problems. -
No luck yet? More tips for troubleshooting viewing issues
-
Contact HST Support access@hstalks.com
-
Please review our troubleshooting guide for tips and advice on resolving your viewing problems.
-
For additional help, please don't hesitate to contact HST support access@hstalks.com
We hope you have enjoyed this limited-length demo
This is a limited length demo talk; you may
login or
review methods of
obtaining more access.
Printable Handouts
Navigable Slide Index
- Introduction
- Talk outline
- Multiple CNS pathways of pain signalling
- Cortical regions that are involved in pain
- Brain imaging to visualize regions activated by pain
- Cortical network activated by pain
- Pain is a complex experience
- Pain activation in ACC and IC
- Cortical regions involved in pain modulation
- Information from cortex to the spinal cord
- Psychological conditions can alter pain
- Attentional state modulates pain
- Shifting attention away from pain
- Distraction from pain makes it weaker
- Pain reduced during distraction
- Attentional modulation in S1 and insular cortex
- Commonly used distraction task
- Heat pain activation when attention to pain
- Cingulofrontal-PAG circuit activated during Stroops
- Emotional state alters pain
- Studies to separate attention and emotions
- Mood and pain
- Mood predicts pain unpleasantness
- Mood alters pain-evoked activity
- Emotional modulation and attentional modulation
- Empathy and pain
- Testing the effect of empathy on pain perception
- High empathy = more pain
- Placebo analgesia
- Effect of a drug is a combination of parameters
- Placebo effects in a number of disorders
- The placebo effect can be created in two ways
- Expectation-induced placebo analgesia
- Imaging placebo analgesia (1)
- Imaging placebo analgesia (2)
- Forebrain involvement in opiate analgesia
- Imaging of opiate analgesia
- PET can determine receptors related to analgesia
- Pain-related opiate binding
- Forebrain dopamine involved in pain modulation
- Dopamine release in response to muscle pain
- Conclusions
- Thank you
Topics Covered
- Involvement of the forebrain in pain perception
- Descending pain control pathways from cortex
- Attentional modulation of pain
- Emotional modulation of pain
- Empathy and pain
- Placebo analgesia
- Role of forebrain opiates and dopamine in analgesia
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Bushnell, M.C. (2009, January 26). Forebrain mechanisms of pain modulation [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 7, 2024, from https://doi.org/10.69645/DJXH2977.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. M. Catherine Bushnell, Speaker's Bureau: Lilly / Grant/Research Support (Principal Investigator): Astra Zeneca.