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1. Epigenetics - introduction
2. Rival hypotheses
3. Thomas Hunt Morgan
4. CH Waddington
5. Ernst Hadorn
6. 3 development features that demand explanation
7. Arthur Riggs
8. DNA methylation
9. Evidence for methylation
10. Isoschizomers and 5-aza-cytidine
11. Definitions of epigenetics
12. "Dual inheritance"
13. Mechanisms other than DNA methylation
14. The epigenome project
15. Summary

Topics Covered

• Introduction to epigenetics
• the leading pioneers in the field of epigenetics
• the basic features of development
• switching and heritability of gene activities
• DNA methylation
• epimutations
• differences between genetics and epigenetics
• genomic imprinting
• chromatin structure
• histone modifications
• the role of RNA in the epigenetic regulation of gene activity
• the bisulfite sequencing technique
• the epigenotype

Links

Series:

• Epigenetics

Categories:

• Biochemistry
• Cell Biology
• Genetics & Epigenetics

Talk Citation

Publication History

• Published on October 1, 2007
• Reviewed on August 12, 2020
• Archived on October 21, 2020

Financial Disclosures

• Dr. Robin Holliday has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.