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1. Introduction
2. Calcium signals: cardiac contraction
3. Intracellular calcium signals
4. Calcium: a versatile and universal messenger
5. The calcium language of cells
6. Cellular sources of calcium
7. "Calciosomes": the ER and mitochondria
8. Cameleon: a GFP/calmodulin based calcium probe
9. Cameleon staining of the ER
10. Cameleon staining of the mitochondria
11. ER and mitochondria dynamics
12. Measuring calcium signals in the ER
13. Mitochondrial calcium signals
14. The mitochondrial calcium paradox
15. The ER-mitochondria connection (1)
16. The ER-mitochondria connection (2)
17. Mitochondria move calcium ions
18. The ER-mitochondria connection (3)
19. Mitochondria sustain ER - calcium refilling
20. The ER/mitochondria calcium cycle
21. Calcium regulates mitochondria
22. Calcium and mitochondrial metabolism
23. Calcium and mitochondrial permeability (1)
24. Calcium and mitochondrial permeability (2)
25. Increasing ER calcium load
26. Effects of ER - calcium overload
27. ER - calcium load and apoptosis
28. Bcl-2 protein family regulates ER calcium content
29. Bcl-2 depletes ER calcium stores
30. Bcl-2 increases ER calcium leak (1)
31. Bcl-2 increases ER calcium leak (2)
32. Protective effect of ER depletion
33. Bax/Bak ablation depletes ER calcium stores
34. SERCA rescues Bax/Bak ablation (1)
35. SERCA rescues Bax/Bak ablation (2)
36. Apoptosis: the calcium connection
37. Regulation of ER calcium load by Bcl-XL
38. Bcl-XL sensitizes the InsP3R calcium channel
39. Bcl-2 discriminates calcium signals

Topics Covered

• Calcium signals: cardiac contraction
• Intracellular calcium signals
• The calcium language of cells
• Cellular sources of calcium
• "Calciosomes": the ER and mitochondria
• Calcium probes
• ER and mitochondria dynamics
• ER calcium signals
• Mitochondrial calcium signals
• Mitochondrial calcium paradox
• The ERmitochondria connection
• Calcium and mitochondrial permeability
• ER calcium load
• Bcl-2 family proteins
• Protective effect of ER depletion
• Bax/Bak ablation
• Apoptosis: the calcium connection

Links

Series:

• The Endoplasmic Reticulum

Categories:

• Cell Biology

Talk Citation

Demaurex, N. (2007, October 1). The endoplasmic reticulum as a calcium gateway in programmed cell death [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 15, 2025, from https://doi.org/10.69645/VAFK9676.
Export Citation (RIS)

Publication History

• Published on October 1, 2007
• Archived on August 13, 2020

Financial Disclosures

• Prof. Nicolas Demaurex has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.