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1. Introduction
2. The impact of childhood stroke
3. Arterial ischemic stroke incidence by age groups
4. Stroke in children differs from stroke in adults
5. Talk outline
6. AIS epidemiology
7. Published stroke incidence rates
8. Canadian pediatric ischemic stroke registry
9. Arterial ischemic stroke epidemiology
10. AIS diagnosis
11. Missing the diagnosis
12. Clinical diagnosis
13. Clinical features of AIS
14. Large vs. small vessel territory AIS
15. Acute stroke neuroimaging
16. Acute stroke neuroimaging: CT insensitive
17. Mechanisms of stroke
18. Childhood AIS major risk factors
19. Cardiogenic mechanism
20. Arteriopathies in pediatric AIS
21. Post-varicella angiopathy and TCA
22. Angiographic characteristics of TCA of childhood
23. Intravascular mechanisms
24. Outcomes and arterial ischemic stroke outcomes
25. Treatments for childhood stroke
26. Recurrent TIA / AIS in children by treatment
27. Antithrombotic vs. anticoagulant therapy
28. Anticoagulants vs. aspirin in AIS
29. Benefit of anticoagulants over aspirin
30. Evidence-based pediatric stroke guidelines
31. CSVT and AIS: current treatment protocol
32. No Reye's syndrome in children on ASA therapy
33. Challenges with tPA in Children
34. Approaching tPA use in children
35. Neuroprotection?
36. Neuroprotective treatments
37. International pediatric stroke study - IPSS (1)
38. International pediatric stroke study - IPSS (2)
39. IPSS enrollment
40. Clinical research methodologies
41. Pediatric AIS treatment trial development (1)
42. Pediatric AIS treatment trial development (2)
43. Future clinical trials: candidate treatments
44. Conclusions

Topics Covered

• Different causes for stroke and approaches to stroke treatment in infants, children and adults
• Often multi-factorial role of anticoagulants
• Different from atherosclerotic adult stroke
• Need for multicentre collaboration to produce evidence on which to base treatment
• Need for early and specific diagnosis and triage to centre with expertise

Links

Series:

• Cerebrovascular Disease

Categories:

• Clinical Practice
• Neuroscience

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on October 27, 2008
• Archived on April 30, 2020

Financial Disclosures

• Dr. Gabrielle deVeber has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.