• Perspective and Pathogenesis
• 23 min
  1. Expanding frontiers of cerebrovascular disease

  • Prof. Vladimir Hachinski
• 32 min
  2. Basic anatomy, physiology and pathophysiology of the cerebral circulation for the physician

  • Prof. Jean-Claude Baron
• 43 min
  3. Pathophysiology of cerebral ischemia

  • Prof. Wolf-Dieter Heiss
• 20 min
  4. Intracerebral hemorrhages: causes and clinical findings

  • Prof. Louis Caplan
• 40 min
  5. Subarachnoid hemorrhage (SAH)

  • Prof. R. Loch Macdonald
• Diagnosis
• 32 min
  6. Clinical diagnosis of stroke and subtypes

  • Prof. Louis Caplan
• 30 min
  7. The investigation of stroke

  • Dr. Bart Demaerschalk
• Treatment
• 35 min
  8. Acute therapy of stroke and reperfusion treatments

  • Prof. Brian Silver
• 39 min
  9. Subarachnoid hemorrhage diagnosis and management

  • Prof. Gary K. Steinberg
• 26 min
  10. Stroke-induced heart injury

  • Dr. Luciano A. Sposato
• Rehabilitation
• 37 min
  11. Stroke rehabilitation: principles of stroke

  • Prof. Robert Teasell
• 27 min
  12. Stroke rehabilitation: therapies and treatments

  • Prof. Robert Teasell
• Prevention
• 23 min
  13. Lifestyle and nutrition in stroke prevention

  • Prof. J. David Spence
• 40 min
  14. Prevention: carotid endarterectomy, angioplasty, and stenting

  • Prof. Brian Hoh
• Special Topics
• 54 min
  15. Pediatric stroke: cerebrovascular injury in the developing brain

  • Prof. Adam Kirton
• 43 min
  16. Stroke in women: epidemiology, risk and prevention

  • Prof. Cheryl Bushnell
• 25 min
  17. Transient ischemic attack and cognition

  • Dr. Jennifer Mandzia
• 31 min
  18. Vascular cognitive impairment

  • Prof. Eric E. Smith
• 34 min
  19. Atrial fibrillation, anticoagulation and vitamins for homocysteine

  • Prof. J. David Spence
• 41 min
  20. Stroke in the young adult

  • Prof. Jeffrey Saver
• 16 min
  21. Stroke in the young

  • Dr. Gyan Kumar
• 23 min
  22. Convergence and joint prevention of stroke and dementia

  • Prof. Vladimir Hachinski
• Archived Lectures *These may not cover the latest advances in the field
• 55 min
  23. Vascular cognitive impairment

  • Dr. John Bowler
• 32 min
  24. Pediatric stroke

  • Dr. Gabrielle deVeber
• 36 min
  25. The deteriorating stroke

  • Prof. Werner Hacke
• 27 min
  26. General management

  • Prof. Bo Norrving
• 35 min
  27. The treatment of stroke: specific management - thrombolysis plus

  • Prof. Nils Wahlgren
• 42 min
  28. Rehabilitation: the chronic phase

  • Prof. Lalit Kalra
• 61 min
  29. Prevention: management of risk and protective factors

  • Prof. Graeme Hankey
• 30 min
  30. Medical therapy for secondary prevention of ischemic stroke

  • Prof. Larry Goldstein
• 34 min
  31. Subarachnoid haemorrhage

  • Prof. Jan van Gijn
• 35 min
  32. Controversies in stroke

  • Prof. Stephen Davies
  • Prof. Geoffrey Donnan
• 35 min
  33. Medical and surgical stroke

  • Prof. Carlos Kase
• 35 min
  34. The urgency of stroke prevention after TIA

  • Prof. S. Claiborne Johnston
• 54 min
  35. Carotid endarterectomy, angioplasty and stenting

  • Prof. Martin Brown
• 42 min
  36. The clinical diagnosis of stroke and stroke subtypes

  • Prof. Louis Caplan

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Global stroke burden
3. Thromboembolic occlusions and ischemic damage
4. Possible interventions
5. Consequences of low blood flow
6. Recanalisation is associated with improvement
7. Time is brain
8. Where do thromboembolic occlusions originate?
9. How can recanalisation be achieved?
10. Pharmacological treatment
11. Pharmacological treatment: alteplase
12. Outcomes of alteplase treatment vs. placebo
13. Importance of delay from stroke onset to treatment
14. SITS-MOST
15. Thrombolysis is safe and effective
16. SITS-MOST univariate analysis results
17. Door to needle time
18. Treatment indications for intravenous rt-PA
19. Comments on usual misunderstandings
20. Treatment beyond European labelling
21. Concern for haemorrhagic complications
22. Risk factors for intracerebral haemorrhage (1)
23. Risk factors for intracerebral haemorrhage (2)
24. Recanalisation intervention beyond 3 hours
25. Recanalisation strategies beyond i.v. thrombolysis
26. HMCAS disappearance after i.v. thrombolysis
27. HMCAS disappearance is important to outcome
28. Thrombectomy using the MERCI device
29. Example for the use of MERCI: background
30. Example for the use of MERCI: the occlusion
31. Example for the use of MERCI: the device location
32. Example for the use of MERCI: recanalisation
33. A clot on the MERCI device
34. Combined iv thrombolysis- thrombectomy strategy
35. Sonothrombolysis
36. Possible hemorrhage and oedema complications
37. Oedema complication
38. Decompressive surgery
39. Functional outcomes of decompressive surgery
40. Risk reduction and odds ratio following surgery
41. Eligibility criteria for the pooled analysis
42. Exclusion criteria
43. Thrombolysis for intracerebral haemorrhage
44. New standards for organised stroke care
45. Summary
46. Thank you for your attention

Topics Covered

• Global stroke burden
• Neurological symptoms
• Where do thromboembolic occlusions originate?
• Recanalization
• Pharmacological treatment
• Clinical trials
• Treatment indications for intravenous rt-PA
• Common misunderstandings
• Treatment recommendations
• Haemorrhagic complications in routine clinical practice
• Multivariate analysis
• Risk factors
• Intravenous thrombolysis
• SITS
• Pooled analysis
• Thrombolysis and highly specialized interventions require new standards for organized stroke care

Links

Series:

• Cerebrovascular Disease

Categories:

• Clinical Practice
• Neuroscience

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on October 27, 2008
• Archived on December 10, 2018

Financial Disclosures

• Prof. Nils Wahlgren has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.