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Welcome to this lecture
on drug shortages,
including their
definition, global trends,
and the range of
medicines affected.
We will examine
key causes such as
manufacturing failures,
supply chain disruptions,
and raw material shortages,
as well as factors like
demand fluctuations
and regulatory challenges.
The consequences of
shortages on patient care,
healthcare providers and
system costs will be explored.
Finally, we will discuss
strategies for prevention,
including stronger
supply chains,
monitoring, and cross
border collaboration.
Drug shortages are a challenge
affecting healthcare
systems worldwide.
Drug shortages occur
when medicine supply
fails to meet clinical demand
for an extended period,
putting patient care and
public health at risk.
Both brief and critical
shortages can disrupt
treatment for various
diseases worldwide,
including the United
States and United Kingdom,
shortages are increasing and
affect generic
branded antibiotics,
cancer therapies, and
injectable drugs.
Understanding the causes of
drug shortages is vital,
as the consequences include
compromised outcomes,
higher costs, and more
medication errors.
Drug shortages are
often caused by
manufacturing failures and
supply chain disruptions.
Pharmaceutical manufacturing
is highly complex,
requiring strict quality
and sterilization.
Failures range from
equipment breakdowns to
contamination and sometimes
entire production lines
must shut down for fixes.
Drug approval ties production to
specific facilities,
making transfers lengthy,
