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Printable Handouts
Navigable Slide Index
- Intro slide
- Motor neurone diseases
- MND: a neurodegenerative disease
- Definition
- Synonyms
- Epidemiology
- Age of onset
- ALS: spinal onset
- Relevant investigations
- ALS: bulbar onset
- Relevant investigations
- Progressive Muscular Atrophy
- Primary Lateral Sclerosis
- Regional variants
- Diagnosis
- El-Escorial Criteria
- Clinical utility of El-Escorial criteria
- Conveying the diagnosis
- Clinical progression
- Natural history of MND/ALS
- Prognostic guides
- One disease or many?
- Molecular neuropathology: Bunina bodies
- Molecular neuropathology: skein-like inclusions
- Hyaline inclusions
- Dystrophic neurites
- Familial ALS/MND
- SOD1 associated ALS/MND
- Clinical follow up
- The Care Team
- Drugs treatments
- Evidence for clinical benefit with riluzole
- Human therapeutic trials
- Treatable symptoms
- Enablement
- Weight loss
- Nutritional management
- Assessment of respiratory function
- Respiratory care
- ALS as a multisystem disease
- Cognitive impairment
- Neuropathology of MND dementia
- Key points
- The future
Topics Covered
- Main clinical subtypes of MND
- Neuropathological features
- Molecular pathology and prognosis
- Multidisciplinary management
- Effectiveness of current drug treatments
Links
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Therapeutic Areas:
Talk Citation
Talbot, K. (2007, October 1). Motor neurone disease: clinical aspects [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved August 31, 2024, from https://doi.org/10.69645/ILZH6528.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Kevin Talbot has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.