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1. Introduction
2. Physical basis of the human genotype
3. Meiosis
4. Recombination - definitions (1)
5. Recombination - definitions (2)
6. Genotype vs. phenotype
7. Genetic loci - definitions (1)
8. Genetic loci - definitions (2)
9. Genetic distance
10. Mendelian segregation (1)
11. Mendelian segregation (2)
12. Dominance and recessiveness
13. Relationship between genotype and phenotype
14. Genotype and phenotype
15. Sickle cell anemia
16. Phenotype - definitions (1)
17. Phenotype - definitions (2)
18. Genotype / phenotype - definitions (1)
19. Genotype / phenotype - definitions (2)
20. Hardy-Weinberg proportions: one autosomal locus
21. Hardy-Weinberg proportions (1)
22. Hardy-Weinberg proportions (2)
23. Heritability
24. Heritability in the broad sense (1)
25. Heritability in the broad sense (2)
26. Heritability in the narrow sense
27. Simple additive polygenic model (1)
28. Simple additive polygenic model (2)
29. Example of additive polygenic model
30. Additive polygenic model: continuous trait
31. Additive polygenic model: binary trait
32. The concept of alleles identical by descent (IBD)
33. Identity by descent
34. Covariance between relatives
35. Locus-specific genetic variance
36. Two main types of linkage analysis
37. Association analysis
38. References

Topics Covered

• Physical basis of the human genotype
• Meiosis
• Genotype vs. phenotype
• Genetic distance
• Mendelian segregation
• Dominance and recessiveness
• Hardy-Weinberg proportions
• Heritability (broad sense and narrow sense)
• Additive polygenic models
• Applications to binary and continuous traits
• Identity-by-descent
• Covariance between relatives
• Locus-specific genetic variance
• Concepts of linkage analysis
• Concepts of association analysis

Links

Series:

• Genetic Epidemiology I

Categories:

• Genetics & Epigenetics
• Methods

Talk Citation

Publication History

• Published on September 1, 2004
• Archived on February 25, 2021

Financial Disclosures

• Prof. Robert Elston has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.