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1. Histone dynamics, heritability and variants
- Dr. Genevieve Almouzni
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2. The RNA polymerase II general transcription machinery
- Prof. Michael Hampsey
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3. Introduction to chromatin structure
- Prof. Karolin Luger
- Archived Lectures *These may not cover the latest advances in the field
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4. Transcription elongation control by RNA polymerase II
- Dr. Ali Shilatifard
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5. The mechanisms and control of mRNA turnover in eukaryotic cells
- Prof. Roy Parker
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6. Coupling transcription, RNA processing and RNA export
- Prof. Grant Hartzog
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7. Dynamic chromatin: ATP-dependent chromatin remodeling machines
- Prof. Bradley Cairns
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8. DNA methylation
- Prof. Steve Jacobsen
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9. Visualization of transcription factor interactions in living cells
- Prof. Tom Kerppola
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10. Accessing and using ENCODE data
- Prof. Peggy Farnham
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11. The beta-globin locus
- Dr. Ann Dean
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13. Transcriptional activation
- Prof. Arnold Berk
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14. The regulation of Pre-Messenger RNA splicing
- Prof. Douglas Black
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15. The E2F family and transcriptional control of the mammalian cell cycle
- Prof. Brian Dynlacht
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16. Genome-wide analyses of protein-DNA interactions
- Prof. Peggy Farnham
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18. Gene silencing by Polycomb complexes
- Prof. Yi Zhang
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19. Eukaryotic gene regulation: from chromatin to transcription to mRNA processing
- Prof. Michael Carey
- Prof. Stephen Smale
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20. Epigenetic information in gene expression and cancer
- Prof. Siavash Kurdistani
Printable Handouts
Navigable Slide Index
- Eukaryotic gene regulation
- General objectives
- Target audience
- Speakers and organization
- Topics
- Transcription initiation and elongation
- Michael Hampsey
- The preinitiation complex
- General transcription factor structure
- Arnie Berk
- Co-activators and RNA pol. II
- Ali Shilatifard
- RNA pol. ll initiation and elongation factors
- RNA processing
- Doug Black
- Splicing mechanism
- Roy Parker
- General pathways of eukaryotic mRNA turnover
- Grant Hartzog
- RNA processing during transcription
- Chromatin and epigenetics l
- Karolin Luger
- The nucleosome at atomic resolution
- Genevieve Almouzni
- CAF-1 stimulates nucleosome formation
- Brad Cairns
- A model for DNA translocation on nucleosomes
- Siavash Kurdistani
- Modifications of histones
- Chromatin and epigenetics ll
- Yi Zhang
- The polycomb EED-EZH2 complex
- Yang Shi
- Purification of a CtBP repressor complex
- Steve Jacobsen
- DNA methylation
- Recent methodological advances
- Tom Kerppola
- Visualization of multiple complexes
- Peggy Farnham
- Analysis of genomic tiling arrays
- Classic gene regulation models
- Brian Dynlacht
- E2F family members
- Ann Dean
- Globin promoters and gene regulation
- Sankar Ghosh
- Signaling pathways leading to NF-kB activation
Topics Covered
- Introduction to the series by Professor Michael Carey and Professor Stephen Smale
Talk Citation
Carey, M. and Smale, S. (2007, October 1). Eukaryotic gene regulation: from chromatin to transcription to mRNA processing [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved May 9, 2025, from https://doi.org/10.69645/YGEQ1639.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Michael Carey has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
- Prof. Stephen Smale has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Eukaryotic gene regulation: from chromatin to transcription to mRNA processing
A selection of talks on Cell Biology
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