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Printable Handouts
Navigable Slide Index
- Introduction
- Overview
- Part 1: bacterial diversity
- Bacteria
- Bacterial structures
- Gram-staining
- Part 2: the burden of bacterial disease
- Bacterial disease: sites in human body
- Burden of disease: causes of death
- Burden of disease: total death by pathogen
- Burden of disease: bacterial infections
- Antimicrobial resistance
- Part 3: why are bacteria able to cause disease?
- Short generation times
- Horizontal gene transfer (HGT)
- Rapid response to environmental fluctuations
- Pathoadaptation
- Importance of transmission
- Infection cycles
- Surface attachment and motility
- Biofilm
- Bacterial toxins
- Bacterial secretion systems
- Intracellularity
- Induction of inflammation
- Part 4: examples of bacterial disease
- Types of bacterial disease – skin and soft tissue
- Scarlet fever
- Types of bacterial disease – respiratory
- Types of bacterial disease – gastrointestinal
- Types of bacterial disease – cardiovascular
- Types of bacterial disease – chronic infection
- Clinical infection – diagnosis and phenotyping
- Part 5: perspectives
- Current and future challenges
- Drug discovery challenges and solutions
- Acknowledgements
Topics Covered
- Bacterial diversity
- The burden of bacterial disease
- Mechanisms of disease caused by bacteria
- Examples of bacterial disease
- Perspectives on epidemiology and drug research
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Neill, D. (2025, August 31). Bacterial diseases [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved September 3, 2025, from https://doi.org/10.69645/KBUI9098.Export Citation (RIS)
Publication History
- Published on August 31, 2025
Financial Disclosures
- There are no commercial/financial matters to disclose.
Other Talks in the Series: Introduction to Clinical Pathology
Transcript
Please wait while the transcript is being prepared...
0:00
Hello.
I'm Daniel Neill.
I'm a senior lecturer
in microbiology
at the University of Dundee.
Today we're going to be talking
about bacterial diseases.
0:12
I've divided today's
talk into five sections.
First we'll cover
bacterial diversity.
Then we'll move on to discuss
the burden of bacterial disease,
a little bit of detail
on disease mechanisms,
and then we'll finish
up with some examples
of bacterial disease
and some perspectives
for the future.
0:30
First part, we'll cover
bacterial diversity.
0:35
Bacteria come in a variety
of shapes and sizes.
What they have in common
is that they're all
prokaryotic microorganisms
and they're ubiquitous
across environments.
Virtually every
ecosystem on Earth
relies on bacteria in
some way, shape or form.
Human history has been
shaped by bacteria.
Although this lecture
will focus on the role
of bacteria as disease
causing organisms,
I wanted to start
by making the point
that they've actually
been fundamental
to the evolution
of life on Earth
and to human life in particular.
Many of the processes
that we rely on
including fermentation,
rely on microorganisms.
Indeed much of the
oxygen in our atmosphere
is produced by cyanobacteria
conducting photosynthesis
in our oceans.
On a fundamental
level for humans,
bacteria are
essential for health
and the human
digestive tract alone
contains more than a 100
trillion bacterial cells.
In the figure on the
left here we can see
three different
characterisations of bacteria
that are based upon morphology.
At the top we can see
the rod shaped bacteria
which are termed the cilli,
in the middle spirochetes
which are these spiral
forms of bacteria,
and at the bottom the cocci.