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Hello. My name is Susan Fairweather-Tait. I'm Professor of Human Nutrition at the Norwich Medical School in the University of East Anglia in the UK. I'm going to be talking to you about iodine.
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Iodine is an obligatory constituent of thyroid hormones and the thyroid hormones are T4, which is thyroxine and T3 triiodothyronine. These are needed for reproduction, for metabolic regulation, for fetal growth and for brain development. Their mechanism of action involves binding to nuclear receptors. These are throughout the body and they alter the gene expression in various cells such as the pituitary, the liver, the heart, the kidney and the brain.
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Most iodine is found in the oceans and iodine ions and seawater are oxidized elemental iodine. This volatilizes in the atmosphere and then it's returned to the soil by rain that contributes the iodine cycle if you like. There's a large variation in the iodine content in drinking water. It's influenced by how far the country is away from the sea when the water is extracted. The soil content varies by geographical location. Iodine deficient soils are found inland and in mountainous regions and areas where there's frequent flooding because that leeches out the iodine from the soil. The soil pH and the amount of organic content will affect the mobilization of iodine into the food chain. The iodine content of foods grown on that soil will vary depending on pH and organic composition. The richest food sources will be marine products obviously from the seawater, fish, shellfish, mollusks and seaweed. Also eggs and milk because the iodine content is affected by feeding and hygiene practices. For example, iodine is added to animal feeds and iodophors are used as a disinfectant in the dairy industry and that will affect the amount of iodine in milk and eggs. Another source of iodine is iodized salt. This is mandatory in many countries that salt has to be iodized where they know there's a public health problem of iodine deficiency. There are legislation to add iodine to salt. Once iodine has been ingested foods containing iodine,

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