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Printable Handouts
Navigable Slide Index
- Introduction
- From what is urine made mostly?
- Kidney structure
- Nephron
- Consider the following question: waste products
- Kidney functions
- What is the glomerular filtration rate (GFR)?
- Kidney reabsorption and secretion
- Glomerulus
- What happens to plasma oncotic pressure?
- Podocytes
- Podocytes zoomed in
- What is the most important force that affects GFR?
- Glomerular filtration rate (GFR)
- The GFR when the afferent arteriole dilates
- The GFR when the efferent arteriole dilates
- Kidney reabsorption, secretion and excretion
- How much plasma does it take to make 2L of urine?
- Plasma to urine
- Kidney solute excretion
- Major urine components
- Solutes throughout the nephron
- Kidney reabsorption & secretion: active/passive transport
- Thank you
Topics Covered
- Anatomy of the kidney
- Overview of renal function
- Glomerular filtration
- Nephron function
- Solute movement through the nephron
- Composition of plasma, glomerular filtrate, and urine
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Briffa, J. (2024, February 29). Renal function: excretory system [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 9, 2024, from https://doi.org/10.69645/FHGL3387.Export Citation (RIS)
Publication History
Financial Disclosures
- There are no commercial/financial matters to disclose.
Other Talks in the Series: Fundamentals of Human Physiology
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, and welcome back to
The Fundamentals of
Human Physiology.
My name is Jessica Briffa
and I'm a postdoctoral fellow in
the Department of
Anatomy and Physiology
at the University of Melbourne
in Melbourne, Australia.
I'll be delivering a series
of four lectures on
kidney function,
where we'll cover
the basic functions
of the kidney in the
first two lectures,
and then go on to the
mechanisms of sodium and
water reabsorption in
the last two lectures.
0:30
Similarly to what Charles
has done in his lectures,
I've also included
these stop and think
questions throughout
my lectures with
the aim to help you track
how you're doing and set
up some ideas for future
questions and activities.
Let's think about this
basic principle in
kidney function as I run down
the timer and then I'll
give you the answer.
What is urine mostly made of?
If you consider that the
kidneys main function is to
filter waste products from
the blood and balance
your body's fluids,
you'll appreciate that urine
is mostly comprised of plasma.
This is because blood filtration
leads to a mass movement of
water and solutes from the
plasma into the renal tubule,
which goes on to form urine.
Approximately 20%
of plasma volume
is filtered at any given time,
which equates to
around 180 litres
of fluid being filtered
by the kidneys daily.
While this is produced by
the filtration of blood,
no blood is typically present in
the urine unless there's an
underlying health condition.
The mechanisms by which
this occurs will be
described in more details
in subsequent slides.