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Printable Handouts
Navigable Slide Index
- Introduction
- Disclosures
- Stroke prevention: keep drugs in perspective
- Importance of lifestyle
- Healthy lifestyle reduced stroke in Swedish women
- Healthy lifestyle reduced CAD in Swedish men
- Managing stroke risk factors
- Nutrition in stroke prevention
- Foods and nutrients that are good for the brain
- Flax seed strains with phytoestrogen
- Naringenin reduces insulin resistance
- Nobiletin prevents diet-induced obesity
- Nobiletin & atherosclerotic plaque formation
- Fruits and vegetables reduce mortality
- Antioxidant supplements don’t work
- Antioxidants give colour and flavour
- So what works?
- Fat and heart disease
- The “good” Mediterranean diet
- Lyon diet heart study
- Spanish Mediterranean diet study
- Dietary cholesterol is important
- The 2015 US cholesterol guidelines
- Diet is the worst part of US lifestyle
- A diet high in animal fat is not the answer!
- Sick populations
- Egg yolks and CHD risk
- Egg yolks
- Saturated fat in meat
- Intestinal microbiome and diet
- TMAO increases stroke/death/MI
- Survival free of atherosclerotic events (egg intake)
- Most North Americans will be vascular patients
- Dietary recommendations for vascular patients
- B vitamins to lower homocysteine
- tHcy≥14 μmol/L by age
- VISP efficacy analysis
- B-Vitamin therapy
- Stroke, MI, death
- Folic acid reduces stroke in 1° prevention
- Results of B vitamin trials
- Meta-analysis: renal function, cyanocobalamin
- Cyanide in cyanocobalamin
- Interesting lessons
- Good news
- Chocolate consumption
- Acknowledgments
Topics Covered
- Stroke risk factors overview and management
- Mediterranean diet benefits in stroke prevention
- Intestinal microbiome and diet effect on atherosclerosis
- Dietary recommendations for vascular patients
- B Vitamins in stroke prevention
Links
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Talk Citation
Spence, J.D. (2017, December 31). Lifestyle and nutrition in stroke prevention [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 9, 2024, from https://doi.org/10.69645/NNHX6620.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. J. David Spence has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Other Talks in the Series: Stroke Prevention
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, I'm David Spence.
I'm professor of neurology and
clinical pharmacology at Western University in London Canada,
and Director of the Stroke Prevention and Atherosclerosis Research Center.
This talk is about lifestyle and nutrition in stroke prevention.
0:17
When disclosures are on this slide and none is relevant to this talk.
0:23
In thinking about stroke prevention it's important to keep
medication which most doctors seem to emphasize in perspective,
medication is only a small part of stroke prevention,
and lifestyle is much more important than most doctors think it is.
When we rank the things we can do to prevent stroke in order of importance,
it's likely that smoking cessation and a Mediterranean diet would rank near the top.
0:47
So, the importance of lifestyle was demonstrated in
this study from the US Public Health study,
and the Nurses Health Study,
43,000 men and 71,000 women followed.
And what this study reported was that persons who followed all healthy lifestyle choices,
which were not smoking,
a moderate intake of alcohol,
a body mass index less than 25,
daily exercise of 30 minutes,
and a diet scored in the top 40 percent had a reduction of stroke by 80 percent.
Now, that was in unhealthy Americans.
1:22
Among Swedish women, Swedish people may be more healthy than Americans.
So, a healthy lifestyle reduced stroke by
62 percent among Swedish women who were healthy at the beginning.
1:35
In Swedish men with hypertension and hyperlipidemia,
all five healthy lifestyle choices
reduced coronary artery disease by more than 80 percent.
So, lifestyle is hugely important.