Peroxisomes and Golgi apparatus as players in Ca2+ homeostasis

Published on November 5, 2013 Reviewed on November 22, 2019   54 min

Other Talks in the Category: Cell Biology

0:00
Hello. My name is Alex Costa. I am a plant biologist and I work at University of Milan in the Department of Biosciences, together with Paola Pizzo from University of Padua department of biomedical sciences. We will talk about peroxisomes and golgi apparatus as players in calcium homeostasis.
0:22
Peroxisomes are organelles present in almost all eukaryotic cells. They are enclosed by a single lipid bilayer membrane and inside the peroxisomal lumen, more than 50 enzymes have been discovered. This enzymes play roles in different metabolic pathways, including fatty acid, beta oxidation, scavenging of hydrogen peroxide, synthesis of etherphospholipids. Peroxisomes are numerous and dispersed throughout the entire cytosol. And their size and number is regulated by a specific transcription factor in mammalian cells. Peroxisomal membrane is impermeable to high molecular weight molecules, and for this reason, specific carriers are expressed in the organelles for taking up different metabolites.
1:20
Peroxisome activity has been linked with many different processes. For example, the peroxisomes have emerged as organelles important in determining cell fate. The activity has been related to cell differentiation processes, embryo development and morphogenesis. Moreover, impairment of peroxisomal activity or biogenesis is linked to different genetic disorders in humans such as Zellweger syndrome spectrum.
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Peroxisomes and Golgi apparatus as players in Ca2+ homeostasis

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