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- Stem Cells
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1. Stem cells: immortality or a healthy old age?
- Dr. Jim McWhir
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2. Mouse embryonic stem cells
- Prof. Sir Martin Evans
- Regenerative Medicine (I)
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3. Stem cells and regenerative medicine
- Prof. Dame Julia Polak
- Dr. Anne Bishop
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4. Tissue engineering: the science, the technology and the industry
- Prof. Robert Nerem
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5. Clinical potential of stem cells
- Prof. John Martin
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6. Genes and cells therapy
- Prof. Nagy Habib
- Regenerative Medicine (II)
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7. Stem cell therapy for the treatment of heart failure
- Dr. James Willerson
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8. Vascular tissue engineering
- Prof. Robert Nerem
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9. Stem cell biology and neurodegenerative diseases
- Dr. Ronald McKay
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10. Cartilage stem cells: tools for joint repair?
- Prof. Charles Archer
- Biotechnology
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11. Stem cell bioprocessing
- Dr. Sakis Mantalaris
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12. Nanotechnology for tissue engineering
- Prof. Thomas J. Webster
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13. Materials for tissue engineering
- Dr. Molly Stevens
- Mr. Julian George
- Commercialization
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14. Commercialisation of stem cells
- Dr. Gareth Roberts
- Ethical and Regulatory Considerations
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15. Stem cell ethics
- Prof. Dame Anne McLaren
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16. The human fertilisation and embryology authority
- Dame Suzi Leather
- Archived Lectures *These may not cover the latest advances in the field
Printable Handouts
Navigable Slide Index
- Introduction
- Stem cells: revolution in medicine
- Organ regeneration - amphibians and mammals
- Translation in order of probable success
- Present results of clinical research
- Different types of multi-potential stem cells
- Novel problems in stem cell translational science
- Traditional pharmacology vs. stem cells repair
- Stem cells repair: the differences between organs
- Mechanism of efficacy
- Animal studies data - for and against stem cells
- Human studies data - for and against stem cells
- Lack of intellectual property
- Cardiac therapeutics: small molecules
- Gene therapy
- Stem cell therapy
- Doctors lead clinical development
- Confusion among regulators
- Interest among politicians: positive and negative
- Present situation
- Female heart transplanted to male:cell infiltration
- The clinical trials - routes of stem cells delivery
- Top Care - AMI studies - protocol
- Top Care study: results
- Top Care study: safety and clinical outcome
- Summary of data from three studies
- Plan for future clinical research
- Gene transfer to stem cells
- Conclusion
Topics Covered
- Amphibians and organ repair
- Application of different cell types to the heart in animal models
- Stem cell repair is complex
- The mechanism of efficacy is unknown
- Intellectual property in autologous stem cells
- Autologous bone marrow cells can cause an increase in ejection fraction after myocardial infarction
- Definitive randomised, controlled, blinded trials are needed
- Gene therapy plus stem cell therapy is the future
Talk Citation
Martin, J. (2007, October 1). Clinical potential of stem cells [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 26, 2024, from https://doi.org/10.69645/LZOU3066.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. John Martin has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.