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See webinar details- Stem Cells
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34 min
1. Stem cells: immortality or a healthy old age?- Dr. Jim McWhir
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40 min
2. Mouse embryonic stem cells- Prof. Sir Martin Evans
- Regenerative Medicine (I)
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26 min
3. Stem cells and regenerative medicine- Prof. Dame Julia Polak
- Dr. Anne Bishop
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27 min
4. Tissue engineering: the science, the technology and the industry- Prof. Robert Nerem
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41 min
5. Clinical potential of stem cells- Prof. John Martin
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11 min
6. Genes and cells therapy- Prof. Nagy Habib
- Regenerative Medicine (II)
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39 min
7. Stem cell therapy for the treatment of heart failure- Dr. James Willerson
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35 min
8. Vascular tissue engineering- Prof. Robert Nerem
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43 min
9. Stem cell biology and neurodegenerative diseases- Dr. Ronald McKay
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17 min
10. Cartilage stem cells: tools for joint repair?- Prof. Charles Archer
- Biotechnology
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46 min
11. Stem cell bioprocessing- Dr. Sakis Mantalaris
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68 min
12. Nanotechnology for tissue engineering- Prof. Thomas J. Webster
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37 min
13. Materials for tissue engineering- Dr. Molly Stevens
- Mr. Julian George
- Commercialization
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36 min
14. Commercialisation of stem cells- Dr. Gareth Roberts
- Ethical and Regulatory Considerations
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44 min
15. Stem cell ethics- Prof. Dame Anne McLaren
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23 min
16. The human fertilisation and embryology authority- Dame Suzi Leather
- Archived Lectures *These may not cover the latest advances in the field
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40 min
Printable Handouts
Navigable Slide Index
- Introduction
- Regenerative medicine - definition
- In vitro 3d constructs
- TERM targets
- Research stages - cells
- Cell sources
- Somatic stem cells
- Embryonic stem cells
- TERM stem cell sources
- Challenge 1 - how to differentiate stem cells
- Medium supplementation
- Differentiation of adult stem cells
- Challenge 2 - key components of medium
- Medium composition for pneumocyte differentiation
- Increased endoderm differentiation
- Challenge 3 - other methods
- Cell extracts
- Normal cell behaviour
- Challenge 4 - microenvironment
- Microenvironment references
- Microenvironment and differentiation
- Challenge 5 - genetic modification
- Gene modulation and differentiation
- Research stages - materials
- Materials for regenerative medicine
- Materials - recent results
- Research stages - scale up
- Challenge 6 - how to produce enough cells
- Bioreactors
- Bioprocess engineering
- Research stages - per-clinical tests
- Challenge 7 - does it work in vivo
- Animal models - for and against
- Cardiac experiments
- Challenge 8 - applicable to humans
- Clinical trials
- Cardiac clinical trials
- Immunocompatibility
- Nucler transfer and human cloning
- Novalung
- Novalung - mechanism of action
- Conclusions
Topics Covered
- Regenerative medicine aims to repair, regenerate or replace damaged tissues and organs
- Selection of appropriate cell sources
- Plasticity
- Differentiation of stem cells towards target phenotypes
- Medium supplementation
- Exposure to cell extracts
- Direct or indirect co-culture with other cells/tissues
- Genetic modification
- Scaffolds
- Bioprocessing systems
- Pre-clinical testing of novel stem cell-based therapies in animal models of disease
- Clinical trials
- Treatment of ischaemic heart failure with autologous bone marrow stem cells
Talk Citation
Polak, J. and Bishop, A. (2007, October 1). Stem cells and regenerative medicine [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 26, 2024, from https://doi.org/10.69645/KTMZ1026.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Dame Julia Polak has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
- Dr. Anne Bishop has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Stem cells and regenerative medicine
Published on October 1, 2007
26 min
