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- Epidemiology and risk factors
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1. Epidemiology of COPD
- Dr. David Mannino
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2. COPD in never smokers
- Dr. Sundeep Salvi
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3. Genetics of chronic obstructive pulmonary disease (COPD)
- Prof. Martin Tobin
- Phenotypes of COPD
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4. COPD and asthma: similarities and differences
- Prof. Peter Barnes
- Pathophysiology and mechanisms of COPD
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5. The pathology of chronic obstructive pulmonary disease
- Prof. James Hogg
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6. The continuum of COPD: a physiological perspective
- Prof. Denis O'Donnell
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7. Inflammatory and immune mechanisms in COPD
- Prof. Peter Barnes
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8. Mechanisms of COPD exacerbations and relation to exacerbation therapy
- Prof. Wisia Wedzicha
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9. Protease-antiprotease balance
- Prof. Robert Stockley
- Therapy and management
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10. Updates in chronic obstructive pulmonary disease (COPD)
- Dr. Omar S. Usmani
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11. Long-acting bronchodilators in COPD
- Prof. Bart Celli
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12. Treatment of COPD exacerbations
- Prof. Antonio Anzueto
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13. Pulmonary rehabilitation: history, promise and problems
- Prof. Richard Casaburi
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14. Lung volume reduction: advances in COPD
- Dr. Nick Hopkinson
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15. New pharmacological therapies for COPD
- Prof. Peter Barnes
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16. The Salford lung study in COPD
- Dr. Dave Leather
- COPD case studies
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17. COPD treatment case I: COPD with “bronchitis attacks”
- Dr. Janwillem Kocks
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18. COPD treatment case II: COPD with asthma as child
- Dr. Janwillem Kocks
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19. COPD treatment case III: COPD with pre-diabetes
- Dr. Janwillem Kocks
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20. Tailoring care for advanced COPD
- Prof. Wissam Chatila
- Archived Lectures *These may not cover the latest advances in the field
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21. Alpha-1 antitrypsin deficiency: state of the art
- Dr. Jamie Stoller
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22. Oxidative stress in COPD
- Prof. William MacNee
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23. Managing co-morbidity in COPD
- Dr. John Hurst
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24. Clinical phenotypes of COPD
- Prof. Jørgen Vestbo
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25. Pulmonary rehabilitation: focusing on rehabilitative exercise
- Prof. Richard Casaburi
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26. Genetics of COPD
- Prof. Ian Hall
Printable Handouts
Navigable Slide Index
- Introduction
- COPD exacerbation
- Respiratory viruses and exacerbation
- Changes in bacterial load
- Exacerbation and bacterial strain change
- Lung microbiome
- Bacteria importance in exacerbation
- Factors that affect treatment
- Oral steroids at COPD exacerbation
- Sputum IL1-beta at bacterial exacerbation
- IP-10a ROC curve analysis
- Virus induce airway inflammation mechanism
- IFN-gamma mRNA and protein deficiency
- Experimental infection interferon production
- Exacerbation recovery
- Fatigue association with COPD exacerbation
- Exacerbation frequency and exercise capacity
- Pulmonary rehabilitation program
- Early pulmonary rehabilitation
- Reduction in exacerbation triggers
- Pollution and COPD exacerbation
- Significance of treatment delay and recovery time
- Symptom onset and early start of therapy
- Exacerbation clustering
- Importance of exacerbation
- Susceptibility to exacerbation
- Association of disease severity with exacerbations
- Factors associated with exacerbation frequency
- The NICE algorithm
- Poet study- salmeterol vs. tiotropium
- Indacaterol
- Rate of moderate and severe exacerbation
- Torch study: analysis by disease severity
- Uplift mild* COPD subgroup: exacerbations
- Inspire study
- Time to first exacerbation
- Roflumilast
- The effect of roflumilast on exacerbations
- Roflumilast significantly reduce exacerbation rate
- Rationale for macrolide use in COPD
- Macrolides - time to first exacerbation
- Symptom duration is responsive to therapy
- Macrolides - sputum markers
- Macrolides (azithromycin) study
- Macrolides study data analysis
- Long term antibiotics
- Bacterial load and airway inflammation
- Sub-group analysis
- Relation of comorbidity to COPD exacerbation
- Beta blockers treatment
- Non-pharmacological interventions
- Optimal care new perspective
Topics Covered
- Definition of exacerbations
- Breakdown of virus directed exacerbations
- Pollution and COPD
- Importance of exacerbations
- Eclipse study
- Poet study
- Torch study
- Inspire study
- Antibiotic use in COPD patients
- Non-pharmacological interventions
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Wedzicha, W. (2012, September 10). Mechanisms of COPD exacerbations and relation to exacerbation therapy [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 21, 2024, from https://doi.org/10.69645/PBRD8172.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Wisia Wedzicha has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
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