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Printable Handouts
Navigable Slide Index
- Introduction
- The aims of this talk
- Why we are interested in imaging in epilepsy
- Imaging commission of ILAE
- Who should undergo imaging?
- Indications for MRI
- How should imaging be best done?
- MRI epilepsy protocol
- What the main findings are
- "CT normal" localisation-related epilepsies
- The most common "pathology" is normal MRI
- Size of the problem: yield of high resolution MRI
- The aims of this talk (2)
- What is PET?
- How does PET work: positron
- How does PET work: radioactive isotopes
- How does PET work: emission
- How does PET work: tomography
- What PET can be used for
- What PET can be used for: metabolic tracers
- Aims: defining the epileptogenic zone
- Epileptogenic lesion
- FDG and FMZ PET in normal MRI TLE
- Volume loss or receptor change?
- FMZ changes in TLE
- FMZ-PET: involvement of the insula
- Prediction of outcome
- Is 11C-Flumazenil-PET clinically useful?
- Imaging co-morbidities
- Imaging genetics
- Ictal 18F-Dopa-PET
- Pitfalls: clinical (functional) imaging (1)
- Pitfalls: clinical (functional) imaging (2)
- Seizure onset zone
- Extratemporal seizure onset
- Ictal symptomatogenic zone
- FDG - PET: correlation with ictal symptoms (1)
- FDG - PET: correlation with ictal symptoms (2)
- Irritative zone
- Diprenorphine binding in MCD
- NMDA receptors: 11C-CNS5161
- FMZ-PET: involvement of the basal ganglia
- Focal epilepsies
- Ictal onset or symptomatogenic zone
- Summary: molecular imaging in epilepsy
Topics Covered
- What is PET and how does it work
- What can PET be used for?
- The clinical impact of PET
- The epileptogenic zone
- Epileptogenic lesion
- Functional deficit zone
- Irritative zone
- Seizure onset zone
- Ictal symptomatogenic zone
- Imaging co-morbidities
- Imaging genetics
Links
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Talk Citation
Koepp, M. (2011, November 1). Molecular imaging in epilepsy [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 7, 2024, from https://doi.org/10.69645/YPDU7761.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Matthias Koepp has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.