• Structure of the blood-brain barrier
• 36 min
  1. The blood-brain barrier in Alzheimer’s disease

  • Dr. Anika Hartz
• 35 min
  2. Tanycytes allow a tight BBB in the median eminence

  • Prof. Esteban Rodriguez
  • Dr. Juan Luis Blazquez
  • Dr. Montserrat Guerra
• Nutrient transport
• 35 min
  3. Blood-brain barrier ion transport

  • Prof. Martha O'Donnell
• Peptides and proteins
• 37 min
  4. Ingestive peptides

  • Prof. William Banks
• 62 min
  5. Blood-brain barrier in health and disease

  • Prof. Thomas Davis
• Overcoming the blood-brain barrier obstacle
• 42 min
  6. Expression vs. function of ABC transporters at the blood-brain barrier

  • Prof. Jean-Michel Scherrmann
• 44 min
  7. The blood-brain barrier and CNS drug development

  • Dr. Danica Stanimirovic
• 34 min
  8. Transport and delivery of neurotrophic peptides and proteins across the BBB

  • Prof. Weihong Pan
• Diseases involving the blood-brain barrier
• 71 min
  9. Inflammation and immune cell entry to the central nervous system

  • Prof. Serge Rivest
• 42 min
  10. The blood-brain barrier in multiple sclerosis: a target for treatment?

  • Dr. Elga de Vries
• 24 min
  11. Ischemic blood-brain barrier and Alzheimer's amyloid plaques development

  • Prof. Ryszard Pluta
• Latest Developments in the Field
• 31 min
  12. MRI approaches for neurovascular imaging

  • Dr. Rick Dijkhuizen
• 33 min
  13. Brain-gut interactions in obesity 1

  • Prof. Weihong Pan
• 19 min
  14. Brain-gut interactions in obesity 2

  • Prof. Weihong Pan
• Archived Lectures *These may not cover the latest advances in the field
• 36 min
  15. Neurotrophins and the BBB

  • Prof. Weihong Pan
• 52 min
  16. Vasoactive peptides and the blood-brain barrier

  • Prof. Maria Deli
  • Prof. Bela Kis
• 42 min
  17. In vivo systems

  • Prof. Quentin Smith
• 46 min
  18. CNS-drug design

  • Prof. Quentin Smith
• 43 min
  19. Brain-to-blood efflux transport of endogenous compounds and its analogue drug at the blood-brain barrier

  • Prof. Tetsuya Terasaki
• 23 min
  20. Stroke and the BBB

  • Prof. Marilyn Cipolla
• 54 min
  21. Barrier mechanisms in the developing brain: mechanisms and misunderstandings

  • Prof. Norman Saunders
• 57 min
  22. Barrier mechanisms in the developing brain: protection or vulnerability?

  • Prof. Norman Saunders
• 43 min
  23. In vitro models of the blood-brain barrier

  • Prof. Pierre-Olivier Couraud
• 41 min
  24. Glucose transport across the blood-brain barrier

  • Prof. Luc Leybaert
• 53 min
  25. The blood-brain barrier and brain tumors

  • Dr. Olaf van Tellingen
• 37 min
  26. Cellular composition of the blood-brain barrier

  • Prof. N. Joan Abbott
• 48 min
  27. Features of mammalian CNS barrier systems

  • Prof. Conrad Johanson

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Imaging neurovascular health and disease
3. MRI scanner cutaway
4. Basic principles of magnetic resonance
5. MRI signal is dependent on protons properties
6. MR contrast agents
7. MRI: a versatile neuroimaging tool
8. Functional MRI
9. BOLD MRI
10. First application of BOLD MRI concept
11. Bold fMRI
12. fMRI applications
13. fMRI after cerebrovascular injury
14. Shifts in motor activation patterns after stroke
15. fMRI studies in laboratory animals
16. Drawbacks in the field of fMRI
17. fMRI - promises, pitfalls and recommendations
18. MRI of the neurovascular unit
19. MRI of blood-brain barrier permeability
20. Contrast enhancement precedes hemorrhage
21. Clinical studies in stroke patients
22. Cellular and molecular MRI
23. Cellular MRI
24. In vivo labeling of macrophages
25. In vitro labeling of cells
26. MRI of macrophage infiltration in ischemic stroke
27. MRI of monocyte infiltration in MS patients
28. Molecular MRI
29. Molecular MRI agents
30. Molecular MRI of cell adhesion molecules
31. Upregulation of cell adhesion detection by MRI
32. Summary
33. Acknowledgements

Topics Covered

• Imaging neurovascular health and disease
• Magnetic Resonance Imaging
• Functional MRI
• Bold MRI
• Function MRI after cerebrovascular injury
• MRI of blood-brain barrier permeability
• Cellular MRI
• Molecular MRI
• MRI of neurovascular unit

Links

Series:

• The Blood-Brain Barrier

Categories:

• Clinical Practice
• Methods
• Neuroscience

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on November 17, 2009

Financial Disclosures

• Dr. Rick Dijkhuizen has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.