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Biomedical Basics

Proteomics

  • Created by Henry Stewart Talks
Published on October 30, 2025   5 min

A selection of talks on Biochemistry

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This presentation will examine Proteomics, with a focus on the fundamentals of proteomics, including its role in connecting genomic information to cellular function and its importance in personalized medicine. We will discuss key technologies such as mass spectrometry for protein identification, along with approaches for measuring protein abundance and analyzing post-translational modifications. The lecture will also highlight advances in quantitative proteomics, functional studies of protein interactions, and the ongoing challenges facing the field. Finally, we will explore the broad applications of proteomics in biomarker discovery, disease research, and translational medicine.. Proteomics is a cornerstone of modern biology that allows us to systematically explore all proteins in cells, tissues, or organisms. Proteomics not only catalogs proteins but also interprets the dynamic proteome shaped by genetics, development, environment, and disease. By investigating protein identities, expression, modifications, and interactions, proteomics links the genome to cellular phenotype. This field is essential for understanding biology at a systems level and plays a pivotal role in advancing personalized medicine and biomarker discovery. Let us now discuss protein identification, a core goal of proteomics, for which mass spectrometry is the main technology. Mass spectrometry allows high-throughput, accurate characterization of proteins in complex samples.

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