From RNA biology to RNA therapeutics
1. What types of RNA do we have in our cells?
By Dr. Douglas Houston – University of Edinburgh, UK
An excerpt from The biochemistry of DNA and RNA 2: biological function
2. How are mRNA molecules normally produced?
By Dr. Carole Sargent – University of Cambridge, UK
An excerpt from Gene structure, expression and regulation: DNA structure and replication
3. How are proteins created from mRNA molecules?
By Dr. Carole Sargent – University of Cambridge, UK
An excerpt from Gene structure, expression and regulation: translation and regulation of gene expression
4. The rise of RNA therapeutics
By Prof. John P. Cooke – Houston Methodist Research Institute, USA
An excerpt from RNA therapeutics: clinical applications and methods of delivery
5. Self-Amplifying RNA: Enhancing vaccine potency at lower doses
By Dr. Anna Blakney – University of British Columbia, Canada
An excerpt from Next-generation RNA vaccines
6. Harnessing mRNA for cancer vaccination
By Dr. Ryan Sullivan – Harvard Medical School, USA
An excerpt from Where are we with mRNA neoantigen vaccinations?