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Printable Handouts
Navigable Slide Index
- Introduction
- Outline
- Definition
- Complete Blood Count (CBC)
- Clinical indicators
- Clinical relevance and insights
- Key components of CBC
- Analysis principles
- Impedance methodology
- RBC/PLT channel
- Classification of anemia
- RBC/PLT channel in detail
- Flow cytometry
- Flow cytometry: Lysing agent
- Flow cytometry: Fluorochrome
- Fluorescence
- Enhanced flow cytometry
- Fluorescence intensity and light scattering
- WBC, NRBC and basophil channel
- Channel for the differentiation of leukocytes (1)
- Channel for the differentiation of leukocytes (2)
- Channel for reticulocytes
- Additional reticulocyte parameters
- Channel for optical platelets
- Channel for immature platelet fraction
- Channel for immature granulocytes
- Immature granulocytes & left shift (1)
- Immature granulocytes & left shift (2)
- Atypical or abnormal lymphocytes
- Complete blood count results: A report
- CBC result: Qualitative,quantitative and morphologic data
- Role of the clinical pathologist in data evaluation: Case reports
- Case study -1 & 2
- Case study 3
- Case study 4
- Case study 5
- The case studies
- Morphologic data
- Research & positional parameters: Potential and applications
- Research and positional parameters
- Positional parameters
- Revisiting case study 1, 3 & 5
- Traditional parameters vs. positional parameters
- Integration of AI in diagnostics (1)
- Integration of AI in diagnostics (2)
- Published evidence on positional parameters
- CBC: The most routine laboratory test worldwide
- Future directions
- Take home message
- Financial disclosures
Topics Covered
- Complete Blood Count (CBC)
- Flow cytometry
- Different channels in flow cytometry for blood sample analysis
- Role of clinical pathologist in data evaluation
- Research and positional parameters
- Integration of AI in diagnostics
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Rolla, R. (2026, May 28). Fundamentals of complete blood count analysis [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved May 29, 2026, from https://doi.org/10.69645/FECF7074.Export Citation (RIS)
Publication History
- Published on May 28, 2026
Financial Disclosures
- No financial relationships or conflicts of interest to disclose.
Other Talks in the Series: Clinical Biochemistry
Transcript
Please wait while the transcript is being prepared...
0:00
Hello. My name is Roberta Rolla.
Today I'm going to talk about
the complete blood count.
It's a cornerstone of clinical
laboratory testing and
provides important insight into
methodological and
systemic health.
0:17
This presentation
provides in-depth
examination of the
complete blood count.
We will first analyze
the most common UCBC
techniques and then
explain how you can apply
this technical knowledge for
accurate interpretation
of the data.
Finally, we will look at
the new research parameters
that are not currently
reported and their
future application.
0:43
The complete blood count
is a routine test that
provides pivotal information for
the diagnosis of
various diseases.
0:54
This slide shows a list of the
main parameters analyzed in
the complete blood
count the units of
measurement and internationally
accepted reference intervals.
Note that the
reference intervals
may vary slightly by
laboratory and population.
As I will explain later,
there are actually
many more parameters
than indicated here.
The complete blood
counter provides
1:19
available diagnostic information
by analyzing various components.
The red blood cell serves as
an important indicator of
conditions such as
anemia, hypoxia,
and polycythemia and provides
important information about
oxygen transport
and overall health.
White blood cells are equally
important and help in the
diagnosis of infection,
inflammatory reactions,
and malignancies as
they reflect the activity
of the immune system.
Platelets play a central role in
the detection of
coagulation disorders and
provide information
about a possible risk
of bleeding or thrombosis.
In addition, new parameters
are now available and
provide deeper insights into
cell morphology
and cell activity.
These parameters are
available for research and
new clinical applications
and they improve
the understanding of
the underlying
pathophysiological processes.
The CBC test provides