Basics of Pharmacology
This learning journey is designed to provide an introduction to fundamental concepts in pharmacology. It covers topics such as absorption, distribution, metabolism, and excretion. Additionally, it delves into subjects related to drug development and pharmacovigilance.
Table of Contents
- Drug development: Safety, efficacy, and druggability
- Drug formulation: Definition, types, and clinical considerations
- Routes of drug administration & bioavailability: principles and impact
- Drug delivery systems and oral delivery challenges
- Drug absorption, First-Pass effect, and Distribution volume
- Drug clearance, metabolism, and excretion: Key principles
- Pharmacodynamics: Drug mechanisms, receptors, and response
- Pharmacogenetics: Genetic variability in drug response
- Adverse drug reactions: Definitions, classification, and risk factors
- Pharmacovigilance and drug safety monitoring
1. Drug development: Safety, efficacy, and druggability
By Prof. Michael Kinch – Stony Brook University, USA
An excerpt from Drug development: from discovery to manufacture
2. Drug formulation: Definition, types, and clinical considerations
By Prof. Dr. Karel Allegaert – KU Leuven, Belgium
An excerpt from Drug formulations
3. Routes of drug administration & bioavailability: principles and impact
By Prof. Dr. Karel Allegaert – KU Leuven, Belgium
An excerpt from Routes of drug administration
4. Drug delivery systems and oral delivery challenges
By Prof. Dr. Sven Stegemann – Graz University of Technology, Austria
An excerpt from Routes of drug delivery
5. Drug absorption, First-Pass effect, and Distribution volume
By Prof. Dr. Karel Allegaert – KU Leuven, Belgium
An excerpt from Bioavailability, absorption and distribution
6. Drug clearance, metabolism, and excretion: Key principles
By Prof. Dr. Karel Allegaert – KU Leuven, Belgium
An excerpt from Metabolism, excretion, and therapeutic window
7. Pharmacodynamics: Drug mechanisms, receptors, and response
By Prof. Dr. Karel Allegaert – KU Leuven, Belgium
An excerpt from Pharmacokinetic/pharmacodynamic integration
8. Pharmacogenetics: Genetic variability in drug response
By Prof. Dr. Karel Allegaert – KU Leuven, Belgium
An excerpt from Pharmacogenetics: an illustration of personalized pharmacotherapy
9. Adverse drug reactions: Definitions, classification, and risk factors
By Prof. Dr. Karel Allegaert – KU Leuven, Belgium
An excerpt from Drug toxicity: mechanisms, interactions, and adverse drug reactions
10. Pharmacovigilance and drug safety monitoring
By Dr. Ulrich Hagemann – International Society of Pharmacovigilance, Germany
An excerpt from The multidimensional landscape of pharmacovigilance: introduction and history