Dr. Hussein Al-Mossawi University of Oxford, UK

1 Talk

Hussein Al-Mossawi is a clinician scientist who trained as a consultant rheumatologist in Oxford and Bristol. His academic work at Oxford has focused on translational immunology. He has worked on understanding the pathological immune responses underlying Spondyloarthritis with a particular interest in the role of GM-CSF in axial and peripheral... read morespondyloarthritis and the role of IL7R genetic polymorphisms in inflammation. Most recently the group has used single-cell technologies such as single-cell RNA sequencing and time-of-flight mass cytometry to gain a deeper understanding of psoriatic arthritis. This work has uncovered the role of clonally expanded CD8 T cells in the inflamed joints and the molecular characteristics that control their activation and trafficking. Together with Laura Coates he set up the Oxford psoriatic arthritis centre where they hold a number of translational grants that seek to inform the understanding of psoriatic arthritis pathobiology and optimise existing treatment therapies. In September 2019, he left full-time academia to take up a role in the pharmaceutical industry, working in immunology research and development.

He is currently an employee of AstraZeneca and continues to hold an honorary research position at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences at the University of Oxford and Oxford University Hospitals NHS trust. Additionally he is a fellow and lecturer in pathology and immunology at St Edmund Hall where he has taught immunology to second year medical students for over 10 years.