Enzymes as Common Therapeutic Targets

To be launched
Dr. Gabriel Barreda-Gómez
CSO, Buscalud Biofarma, Spain
Summary

Enzymes are essential proteins in living organisms that catalyse biochemical reactions with high selectivity and efficiency. Their activity is heavily reliant on the integrity of their native protein conformation. When mutations occur, this conformation can be altered, leading to impaired enzyme function and the onset of various diseases. As a... read moreresult, an increasing number of therapies have been developed to alleviate the effects of dysfunctional enzymes.

This series of lectures will comprehensively cover the diverse and pivotal roles that enzymes play in health and disease, with a special focus on their therapeutic applications. The lectures will examine enzymes’ biological mechanisms, their involvement in metabolic, genetic, cardiovascular, and neurodegenerative disorders, and their potential in cancer therapy, immunotherapy, and inflammation control. Speakers will also address cutting-edge developments in enzyme replacement therapy (ERT), gene therapy, and the role of enzymes in drug resistance. By exploring real-world case studies, clinical outcomes, and the latest advancements in enzyme-based treatments, these talks will offer a deep understanding of the challenges and future trends in enzyme-targeted therapies across various medical fields.

In summary, by the end of this series, the audience will gain insights into the current landscape of enzyme research, the challenges faced in clinical applications, and the future directions in enzyme-based therapies.