Gene Manipulation - How and Why?

To be launched
Dr. Sidi Chen
Yale University School of Medicine, USA
Summary

The "Gene Manipulation - How and Why?" lecture series offers a comprehensive exploration of genetic engineering, covering the fundamental techniques and their transformative applications across biomedical science. Beginning with the basics of gene cloning and genetic modification, the series aims to guide learners through both the foundational principles and cutting-edge... read moreadvancements in gene manipulation. Each lecture is carefully crafted to address key methods—such as recombinant DNA, RNA interference, and CRISPR-Cas9—that have revolutionized the ways in which genes are edited, silenced, or expressed to achieve desired outcomes. By providing in-depth discussions on these techniques, the series lays a robust foundation for understanding how gene manipulation can unravel complex biological questions and create novel therapeutic strategies.

This series extends beyond the technical aspects to explore practical and ethical implications of gene manipulation. Lectures include topics such as developing gene-based therapies for genetic disorders, enhancing immune responses in cancer immunotherapy, and constructing animal models for disease research. The program also critically examines emerging issues, including the ethical boundaries of gene editing in humans, especially concerning germline modifications and synthetic biology. With a diverse set of topics ranging from cancer immunology to gene-editing tools and ethical considerations, this series equips students and researchers with both the knowledge and critical thinking skills necessary to engage in the evolving landscape of genetic science.