Nuclear Receptors as Common Therapeutic Targets

The lecture series will introduce the family of nuclear receptors which act as ligand-activated transcription factors. The first part of the series will cover the general background of the nuclear receptor family including classification, physiological importance, structure & function, mechanisms of modulation, and natural ligands, to generate broad understanding of... read morenuclear receptor roles and function. The second part will present the 48 human nuclear receptors individually or in functionally related groups together with their biological roles, available ligands/drugs, therapeutic relevance and future potential.