Biochemistry of metabolism (part 2)
This learning journey builds on the foundational concepts of energy metabolism by exploring the advanced processes that make up the cellular metabolic network. It covers amino acid catabolism and nitrogen disposal via the urea cycle, oxidative phosphorylation and electron transport, and the mechanism of ATP synthesis. It also examines anabolic pathways, such as gluconeogenesis, and introduces the concept of substrate cycling, illustrating how cells finely balance energy production and consumption to maintain metabolic homeostasis.
1. Amino acid catabolism
By Prof. Gerald W. Feigenson – Cornell University, USA
An excerpt from Urea cycle; oxidative phosphorylation 1
2. Urea cycle: a closer look
By Prof. Gerald W. Feigenson – Cornell University, USA
An excerpt from Urea cycle; oxidative phosphorylation 1
3. Last stage of energetics metabolism: Oxidative phosphorylation
By Prof. Gerald W. Feigenson – Cornell University, USA
An excerpt from Urea cycle; oxidative phosphorylation 1
4. What happens during electron transport?
By Prof. Gerald W. Feigenson – Cornell University, USA
An excerpt from Urea cycle; oxidative phosphorylation 2
5. ATP synthesis: a binding site change model
By Prof. Gerald W. Feigenson – Cornell University, USA
An excerpt from Urea cycle; oxidative phosphorylation 2
6. Anabolism: Gluconeogenesis
By Prof. Gerald W. Feigenson – Cornell University, USA
An excerpt from Gluconeogenesis and the Calvin cycle
7. The concept of ‘substrate cycling’
By Prof. Gerald W. Feigenson – Cornell University, USA
An excerpt from Gluconeogenesis and the Calvin cycle