Dr. David Friel Case Western Reserve University, USA

2 Talks

David Friel completed a PhD in biophysics at the University of Chicago and received postdoctoral training with Dr. Bruce Bean and subsequently with Dr. Richard Tsien before joining the Neurosciences Department at Case Western Reserve University where he established his own laboratory. Dr. Friel is interested in Calcium signaling mechanisms... read morein excitable cells, with an emphasis on understanding how the interplay between voltage-sensitive Calcium entry and Calcium uptake and release by intracellular stores such as mitochondria and the endoplasmic reticulum regulates Calcium levels in different cellular regions, and how this controls Calcium- sensitive processes within cells and neural circuits. His current work focuses on the impact of P/Q-type Calcium channel mutations on Calcium homeostasis, membrane excitability and synaptic communication in cells and circuits that participate in cerebellar motor control.