Prof. Shiv Pillai Harvard Medical School, USA

2 Talks

Shiv Pillai MBBS, PhD is a Professor of Medicine at Harvard Medical School is the Director of an NIH Funded Autoimmune Center of Excellence at Massachusetts General Hospital, the Director of the Harvard Immunology PhD program and a Member of the Ragon Institute of MGH, MIT and Harvard.
Dr.... read morePillai coined the term “surrogate light chains” for proteins that he identified, as part of a novel receptor, now known as the pre-B receptor. His laboratory also showed that Btk, the product of the gene mutated in X-linked agammaglobulinemia, is functionally linked to the pre-B receptor and the B cell receptor. Btk inhibitors are now widely used in lymphoid malignancies and autoimmunity. One area of current interest is in pathogenic mechanisms that are of importance in systemic sclerosis and IgG4-related disease, Dr. Pillai is the co-author of two widely used textbooks of immunology.