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Prof. Carl-Henrik Heldin Ludwig Institute of Cancer Research, Sweden1 Series
C.-H. Heldin is since 1986 the Branch Director of the Ludwig Institute for Cancer Research in Uppsala, Sweden, and since 1992 also professor in Molecular Cell Biology at Uppsala University. He was born in 1952, and obtained a PhD degree in Medical and Physiological Chemistry in 1980 at the University... read moreof Uppsala, where he continued to work until 1985 using a position sponsored by the Swedish Cancer Society. The research interest of C.-H. Heldin is related to the mechanisms of signal transduction by growth regulatory factors, as well as their normal function and role in disease. In particular, platelet-derived growth factor (PDGF), a major mitogen for connective tissue cells, and transforming growth factor beta (TGF beta), which inhibits the growth of most cell types, are studied. An important goal is to explore the possible clinical utility of signal transduction antagonists.