Dr. Ines Pineda-Torra Division of Medicine University College London, UK1 Talk
Ines Pineda-Torra is a Professor in Cardiometabolic Medicine at University College London, UK. Her research career to date has mainly focused on the knowledge of the different aspects of nuclear receptor function as transcriptional regulators involved in the control of lipid metabolism. As an undergraduate student with a EU ERASMUS... read moreFellowship, she worked at the Center for Biomembranes and Lipid Enzymology at the University of Utrecht (The Netherlands) in the laboratory of Prof Van den Bosch to characterize the effect of aspirin on the regulation of IL-1ß-induced phospholipase A2. Her work on the transcriptional regulation of gene expression by nuclear receptors started in the laboratory of Prof Bart Staels at the Pasteur Institute of Lille (France) as a recipient of a predoctoral Marie Curie grant. The primary goal of her research was to determine the molecular mechanisms governing the expression of the nuclear receptor peroxisome proliferator-activated receptor (PPAR) PPARalpha. Subsequently, as a postdoctoral fellow in the laboratory of Dr Freedman at the Memorial Sloan-Kettering Cancer Center (USA), she determined the impact of the recruitment of the DRIP coactivator complex (identified in Dr. Freedman’s group) on the activity of the bile acid receptor FXR. In Dr Garabedian´s laboratory at the New York University School of Medicine (USA) she initiated and developed a novel research line aimed to uncover the role of phosphorylation on the lipid-activated nuclear receptor LXR alpha function in macrophages. In 2008 she joined the Division of Medicine at UCL as a non-clinical Lecturer in the Centre for Clinical Pharmacology. In 2013 she was promoted to Senior Lecturer, now Associate Professor in the scheme.