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Prof. David Rubinsztein Cambridge Institute for Medical Research, UK2 Talks
David C Rubinsztein, M.B. Ch.B; B.Sc. (Med) Hons; Ph.D., FRCPath, FMedSci, FRS, is a UK Dementia Research Institute Professor, Professor of Molecular Neurogenetics at the University of Cambridge, Deputy Director of the Cambridge Institute for Medical Research and Academic Lead of the Alzheimer’s Research Cambridge Drug Discovery Institute. He has... read morebeen a leader in the field of autophagy, particularly in the context of neurodegenerative diseases. His laboratory pioneered the strategy of autophagy upregulation as a possible therapeutic approach in various neurodegenerative diseases and has identified drugs and novel pathways that may be exploited for this objective. He has made key contributions to illuminating the relevance of autophagy defects as a disease mechanism and to the basic cell biology of this important catabolic process. His laboratory has also identified druggable pathways independent of autophagy that may be relevant to diseases caused by aggregate-prone proteins. These insights into a fundamental catabolic process open novel avenues for developing potential therapies.
Rubinsztein has been elected as a Fellow of the Royal Society, Fellow of the Academy of Medical Sciences, and as an EMBO member. He was awarded the Graham Bull Prize for Clinical Science (Royal College of Physicians), the Thudichum Medal (Biochemical Society) and the Roger the Spoelberch Prize for his contributions.