The strategic role of blockchain-enabled federated learning, AI agents and dynamic capabilities in driving pharmaceutical operational advantages
Abstract
This paper explores the strategic integration of artificial intelligence, blockchain technology and dynamic capabilities (DC) in the pharmaceutical sector. The research utilises a mixed-methods approach that integrates quantitative benchmarking and case studies of six organisations to elucidate the operational realities of technology adoption. The primary findings suggest that a substantial financial investment does not necessarily result in a positive return on investment. Instead, the analysis identifies distinct strategic archetypes, ranging from ‘foundation builders’, characterised by the presence of substantial yet underutilised infrastructure, to ‘lean innovators’, who demonstrate high efficiency with minimal expenditure. A central conclusion of this paper is that DC is the critical enabler that allows companies to translate technological potential into tangible value. Pharmaceutical organisations with robust DCs exhibit considerably higher project success rates and more adeptly leverage their skilled workforce to enhance operational efficiency. The paper provides a data-driven framework for benchmarking these strategic approaches, demonstrating that competitive advantage hinges on aligning technological investments with robust organisational capabilities. This article is also included in The Business & Management Collection which can be accessed at https://hstalks.com/business/.
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Author's Biography
Antonio Pesqueira is a leading voice in healthcare and pharmaceutical operations, driving digital transformation across commercial and supply chain functions. Over 15 years, he has specialised in integrating advanced technologies (artificial intelligence [AI]/machine learning), enterprise platforms (systems applications and products/SalesforceDotCom) and agile methodologies to optimise complex global operations. In parallel, as a Professor and Research Fellow at University Institute of Lisbon, Antonio plays a pivotal role in the PhD programme, focusing his research on generative AI, Agent2Agent Protocols, blockchain and data management to enable compliant, autonomous supply chains and Compliance as a Service. A prolific author of over 20 scholarly articles in journals such as Journal of Business Research, Information Systems Frontiers, he is also a respected reviewer for ‘Discover Artificial Intelligence’ (Springer Nature), ‘Pharmaceutical Medicine’ and ‘BMC Medical Informatics and Decision Making’. Antonio’s thought leadership extends to chairing the Pharmaceutical Supply Chain & Security World Forum and keynote speaking at major industry events. His expertise is further highlighted by certifications in Data Science and Agile Coaching, and his service on the Scientific Review Committee for FUTURES 2025.