Henry Stewart Talks

The Biomedical & Life Sciences Collection

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Welcome to The Biomedical & Life Sciences Collection

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This collection of specially prepared animated audio visual presentations with synchronized narration is regularly updated and growing with over 1,500 talks.

RECENTLY ADDED TALKS  View All

Play 'Is there a role for academia in drug discovery'
Is there a role for academia in drug discovery More info
Dr. Adrian J. Ivinson

TOPICS COVERED IN THIS TALK

  • Increasing numbers of neurological disorders correlates with the growing numbers of elderly
  • Paucity of drugs that treat these neurological disorders
  • Reasons for this failure
  • Need to reassess the traditional division of labor between the for-profit sector and the not-for-profit academic sector
  • Transfer of the discovery phase to academia?
  • Other aspects of the heretofore-failed neuro drug discovery pipeline e.g. large-scale genetic studies aimed at unearthing new targets
  • The need to redefine the precompetitive space
  • The need to build new collaborations between companies, and between the commercial and academic sectors
Play 'Drug resistance in tuberculosis and its public health management'
Drug resistance in tuberculosis and its public health management More info
Dr. Paul Nunn

TOPICS COVERED IN THIS TALK

  • Definition of common terms
  • The rationale for addressing drug resistance
  • The size and distribution of the drug resistance epidemic in TB
  • Global level plans for addressing it
  • National level plans and implementation
  • Obstacles and conclusions
  • Sources for further study of the policy background

CATEGORIES

Biochemistry
Cancer
Cell Biology
Diseases, Disorders & Treatments
Drug Discovery
Genetics
Immunology
Methods
Microbiology & Virology
Neurobiology
Pharmaceutical Science

RECENTLY ADDED SERIES  View All

SOPs for Regulatory Applications for the Pharmaceutical Industry
Diabetes in Perspective
Drug Discovery and Development in the Neurosciences
Tuberculosis
Glycobiology
The discovery of glycan function and its fundamental applications
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FREE TALK OF THE MONTH

Play 'Diagnosis and screening of diabetes'
Diagnosis and screening of diabetes More info
Prof. Jonathan Shaw

TOPICS COVERED IN THIS TALK

  • Define glucose levels for diabetes diagnosis
  • Retinopathy and glycaemia
  • Limitations of glucose measurement
  • Limitations of HbA1c measurement
  • Screening for diabetes with questionnaires

POPULAR TALKS

Play 'The Impact of astrocyte mitochondrial ATP production on neuroprotection after stroke'
The Impact of astrocyte mitochondrial ATP production on neuroprotection after stroke More info
Prof. James Lechleiter

TOPICS COVERED IN THIS TALK

  • Schematic diagram of an ischemic stroke at cellular level
  • P2Y1-R stimulation
  • Photothrombosis
  • Pathways involved in ATP production in astrocytes
  • Working model of astrocyte neuroprotection
  • Ischemia-induced astrocyte cell swelling
Play 'A paradigm shift in the brain-immune relationships: Infiltrating macrophages in central nervous system repair'
A paradigm shift in the brain-immune relationships: Infiltrating macrophages in central nervous system repair More info
Prof. Michal Schwartz

TOPICS COVERED IN THIS TALK

  • The CNS immune enigma
  • CNS response to injury
  • Recruitment of macrophages is insufficient
  • Site, dose, timing for macrophage implantation
  • Local and systemic immune response
  • Circulating T cells are needed for recovery
  • Protective autoimmunity vs. autoimmune disease
  • Two faces of macrophages
  • Creation of chimeric mice with head protection
  • Macrophages play anti-inflammatory role
  • Transferred monocytes promote repair
  • T-cells boost monocyte recruitment
  • Macrophages resolve microglia response
  • The glial scar regulates microglia / macrophages
  • CSPG production and degradation
  • CSPG and the IL-10 expressing monocytes
  • Co-localization of macrophages with the glial scar
  • Location determines macrophage phenotype
  • Macrophages and neuroprotection in the retina
  • Macrophages support progenitor cell renewal
  • Monocyte recruitment is limited
  • Type, phenotype, location, timing
  • Neurogenesis: highest manifestation of plasticity
  • CNS specific autoreactive T cells
  • Spatial memory
  • The immunological malfunction
  • Immunity to self and self-maintenance
  • Local and systemic inflammation
  • Circulating cells fight local inflammation
  • Recruitment of monocytes in Alzheimer
  • From immune deficiency to brain malfunction
Play 'Physiology of innate immunity'
Physiology of innate immunity More info
Prof. Keith W. Kelley

TOPICS COVERED IN THIS TALK

  • The varied roles innate immune cells play in physiology of the entire body
  • The role of mononuclear myeloid cells in immunophysiology
  • Neuroendocrine stress responses
  • Appetite
  • Fever
  • Sleep
  • Cognition
  • Pain and sickness
  • Depression

TESTIMONIALS

"The quality of The Biomedical & Life Sciences Collection is second to none in my experience of the biomedical field for nearly four decades!! Well done indeed."
Prof. Herb Sewell, Pro Vice Chancellor
University of Nottingham