Henry Stewart Talks
The Biomedical & Life Sciences Collection
Online Seminars By Leading World Experts

Welcome to The Biomedical & Life Sciences Collection

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This collection of specially prepared animated audio visual presentations with synchronized narration is regularly updated and growing with over 1,500 talks.


Play 'Epidemiology of Osteoporosis'
Epidemiology of Osteoporosis More info
Prof. Cyrus Cooper


  • Overview of osteoporosis
  • Impact of osteoporosis related fractures
  • Prevalence and treatment of osteoporosis related fractures
  • Vertebral fractures and osteoporosis
  • Trends in incidence of hip fractures
  • Fracture risk factors in adulthood
  • Fracture risk factors in childhood and development
  • "Capture the Fracture" IOF campain
Play 'Interactome networks and human disease'


  • Linear genotype-phenotype relations
  • Genotype and phenotype of eye color
  • Complex genotype-to-phenotype relationships
  • Cells as complex wiring diagrams of interaction
  • Types and properties of interactome networks
  • Network properties required for biological functions
  • Interactome mapping
  • Edgotype
  • Why systematic maps of interactome networks are important
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Play 'AMPA-receptors and fast synaptic transmission in the brain'
AMPA-receptors and fast synaptic transmission in the brain More info
Prof. Stuart Cull-Candy


  • The fast component of excitatory synaptic transmission in the brain mediated by AMPARs
  • Functionally distinct AMPAR subtypes are involved in transmission (importance of topology)
  • How AMPAR diversity shapes transmission (implications of differential distribution and plasticity)
  • How AMPAR structure affects its behaviour and properties
  • Role of auxiliary AMPAR proteins (stargazin) in controlling AMPAR properties and diversity


Play 'Gene therapy and virotherapy in the treatment of cancer'
Gene therapy and virotherapy in the treatment of cancer More info
Prof. Leonard Seymour


  • Mutations and microenvironment in cancer
  • The challenge of cancer gene therapy
  • Cancer gene therapy strategies: p53 and TNF
  • Virotherapy against tumour cells
  • Virotherapy studies with wild-type vs. genetically-engineered viruses (Adenovirus, Vaccinia & Herpes)
  • Future of cancer virotherapy
Play 'Understanding poor Lymphatic function and how to improve it: Revisiting old facts and examining new leads to help wounds heal'
Understanding poor Lymphatic function and how to improve it: Revisiting old facts and examining new leads to help wounds heal More info
Prof. Neil Piller


  • Lymphoedema and oedema: key differences
  • Blood-tissue-lymph systems and their interfaces
  • Importance of the lymphatic system
  • Organization of superficial lymph system
  • Functioning of the lymphatic system
  • Consequences of poor lymph flow
  • Deep and superficial systems
  • The adipo-lymphatic connection
  • Fats in the diet: How they affect lymph flow and load
  • Lymphatic drainage from the small intestine
  • Blockage/overload and chylous reflux
  • Factors which determine lymph load and flow
  • Development of lymphoedema
  • Types of lymphoedemas
  • Increased subcutaneous fat reduces lymph transport
  • Build-up of fibrous tissues reduces lymphatic function
  • The problems of fibrosis
  • Proximity issues
  • Other limb swellings which look like lymphoedema which may underlie the wound area: Lipoedemas, Myxoedema and Phlebo-lymphoedema
  • Adipose tissue, fibrosis and lymphoedema
  • What can be done to improve tissue/cell health and improve wound healing?
Play 'The genetic basis of kidney cancer'
The genetic basis of kidney cancer More info
Dr. W. Marston Linehan


  • Renal Carcinoma
  • Stage I , Stage IV kidney cancer
  • Human Renal Epithelial Neoplasms
  • Loss of alleles in renal cell carcinoma
  • Mapping the Minimal 3p Loss Region in Clear Cell Renal Carcinoma
  • Studying Cancer Families to Identify Renal Carcinoma Genes
  • Identification of Kidney Cancer Genes
  • Inherited Forms of Renal Carcinoma
  • Clear Cell Renal Carcinoma: von Hippel Lindau (VHL)
  • VHL Gene
  • VHL Gene Localization Map
  • Germline VHL Mutations
  • Papillary Renal Carcinoma
  • Mouse Studies of VHL gene
  • VHL Gene Function
  • HIFα
  • Downstream effects of VHL mutation
  • Targeting VHL/HIF in Clear Cell RCC
  • TCGA Clear Cell Kidney Cancer
  • Intratumor Heterogeneity
  • Warburg effect in clear cell kidney cancer
  • Non-Clear Cell RCC
  • Locally Advanced Kidney Cancer
  • Hereditary Papillary Renal Carcinoma (HPRC)
  • Inherited Renal Carcinoma
  • Type 1 Papillary Renal Carcinoma
  • Penetrance of MET Mutation H1210R
  • MET Gene: Type 1 Papillary RCC
  • Location of the HPRC Gene
  • HPRC: Activating Mutations in the Tyrosine Kinase Domain of MET
  • Location of MET Mutations in the HPRC Patients
  • Targeting MET RCC Gene Pathway
  • Potential Small Molecule Target: MET Tyrosine Kinase Inhibition
  • Foretinib: Dual VEGFR and MET Inhibitor
  • MiT Kidney Cancer TFE3, TFEB, MITF
  • UOK124, Papillary Kidney Cancer
  • UOK124, UOK120, UOK 146 & TFE3 Kidney Cancer
  • Inherited Renal Carcinoma Birt-Hogg-Dubé (BHD)
  • Birt Hogg Dubé Cutaneous Manifestations
  • Kidney Tumors in BHD
  • BHD Renal Tumor Pathology
  • BHD Lung Cysts
  • Identification of the BHD Gene
  • Cutaneous Fibrofolliculomas
  • BHD Gene: Chromophobe RCC
  • BHD Gene Locus: Chromosome 17
  • BHD Protein Sequence
  • FLCN Mutation Spectrum
  • Therapeutic Approach: What Kind of Gene is FLCN?
  • BHD Gene Analysis in BHD-Associated RCC
  • Somatic mutations in renal tumors from BHD patients
  • UOK 257, BHD -/- RCC cell line Study
  • How Does the FLCN Gene Function?
  • Folliculin-FNIP1/2-AMPK Interactions
  • mTORC1/mTORC2 Activation: FLCN-Deficient Kidney Cancer
  • BHD Deletion Specifically in the Kidney
  • BHDf/d/KSPCre Mouse Kidney Study
  • Hereditary Leiomyomatosis Renal Cell Carcinoma (HLRCC)
  • HLRCC: Cutaneous Manifestations, Uterine Leiomyomas
  • HLRCC: Papillary Kidney Cancer Type 2
  • Orangophilic Nucleoli + Perinucleolar Halos
  • Fumarate Hydratase Gene: HLRCC
  • UOK-262 Study
  • Loss of a Krebs Cycle Enzyme Can Lead to Kidney Cancer
  • Impaired citric acid cycle and “Warburg effect”
  • HLRCC-Renal Cancer: Glucose-Dependent
  • PET Scan
  • HLRCC novel treatment approaches
  • Kidney Cancer: a Metabolic Disease


"I have followed this collection for over a year. It is a fantastic series of lectures. One of the best things that has happened in education."
Prof. David Givol
Weizmann Institute, Israel

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