Henry Stewart Talks

The Biomedical & Life Sciences Collection

Online Seminars By Leading World Experts
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Welcome to The Biomedical & Life Sciences Collection

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This collection of specially prepared animated audio visual presentations with synchronized narration is regularly updated and growing with over 1,500 talks.

RECENTLY ADDED TALKS  View All

Play 'Presynaptic plasticity'
Presynaptic plasticity More info
Prof. Robert S. Zucker

TOPICS COVERED IN THIS TALK

  • What is short-term synaptic plasticity?
  • Use of quantal analysis to show that plasticity arises presynaptically
  • Synaptic depression and the "Depletion Model"
  • Relationship of depletion model parameters to binomial statistical parameters
  • Refinements to the depletion hypothesis
  • Origin of slow phases of depression
  • Role of multiple vesicle pools
  • Role of vesicle endocytosis
  • Role for calcium in recovery
  • Why depression is sometimes absent
  • Other forms of depression
  • Phases of synaptic enhancement: facilitation, augmentation, and potentiation
  • Presynaptic electrical events in synaptic enhancement
  • Calcium and the nonlinear summation single site hypothesis
  • Kinetic components of calcium removal
  • Multiple sites of calcium action
  • Problems with identifying molecular mediators
  • Candidate molecular mediators
  • A comprehensive model of presynaptic plasticity
  • Other forms of synaptic enhancement
  • Computational roles of short-term synaptic plasticity
  • Physiological roles of short-term synaptic plasticity
Play 'Stem cells derived from amniotic fluid and placenta'

TOPICS COVERED IN THIS TALK

  • Introduction to the amniotic fluid and placenta
  • Collecting stem cells from the amniotic fluid or placenta
  • Cell markers in amniotic fluid or placenta derived stem cells
  • Amniotic fluid or placenta derived stem cells are able to form embryoid bodies
  • Uses of amniotic fluid or placenta derived stem cells: Immunomodulation
  • Uses of amniotic fluid or placenta derived stem cells: Regenerative medicine
  • Amniotic fluid or placenta derived stem cells can be differentiated into a variety of cell types
  • Amniotic fluid stems cells in the kidney
  • Necrotizing enterocolitis; a model and treatment with amniotic fluid stems cells
  • Clinical uses of amniotic fluid or placenta derived stem cells
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Play 'The genetics of frontotemporal dementia'
The genetics of frontotemporal dementia More info
Prof. John Hardy

TOPICS COVERED IN THIS TALK

  • Overall characteristics of FTD
  • Genes involved in frontotemporal dementia
  • Pathology of frontotemporal dementia
  • FTDP-17: 3R and 4R-tauopathies
  • FTLD-TDP subtypes
  • MAPT as the gene for FTD with tangles
  • The microtubule associated protein tau
  • Mutations affecting tau protein in FTD
  • PGRN mutations as a cause for FTD
  • A major locus for FTD and ALS on chromosome 9
  • Chromosome 3 dementia
  • Making sense of these genes

POPULAR TALKS

Play 'G-Protein coupled receptors in drug discovery'
G-Protein coupled receptors in drug discovery More info
Dr. Mark Wigglesworth

TOPICS COVERED IN THIS TALK

  • The G-protein coupled receptor superfamily
  • GPCRs as drug targets
  • Approved GPCR drugs
  • why the reduction in GPCR drugs
  • new screening technologies and new drug targets
Play 'Barrier mechanisms in the developing brain: protection or vulnerability?'
Barrier mechanisms in the developing brain: protection or vulnerability? More info
Prof. Norman Saunders

TOPICS COVERED IN THIS TALK

  • The brain develops within a well-defined internal environment
  • The properties of this internal environment are determined by transporters in the cellular interfaces between the blood, brain and cerebrospinal fluid
  • The transporters are effective because the intercellular spaces between the cells in the interfaces are sealed by tight junctions
  • The transporters are both influx and efflux and many are active very early in brain development
  • Although brain barrier mechanisms are present very early in development they are vulnerable to pathological conditions e.g. inflammation, which may result in barrier dysfunction and damage to the fragile developing brain
  • These mechanisms thus provide protection and a stable internal environment, but some may render the developing brain more vulnerable e. g. inward transport of toxins such as mercury via a normal amino acid transporter
Play 'Plant cell wall: structure and biosynthesis'
Plant cell wall: structure and biosynthesis More info
Prof. Debra Mohnen
Dr. Melani A. Atmodjo

TOPICS COVERED IN THIS TALK

  • Overview of plant cell wall functions
  • Primary and secondary walls
  • Types of polymers in plant cell walls
  • Organization of plant cell walls / plant cell wall models
  • Cell wall proteins
  • Structure and synthesis of lignin
  • Structure and synthesis of cellulose
  • Structure and synthesis of hemicelluloses
  • Structure and synthesis of pectic polysaccharides

TESTIMONIALS

"I have followed this collection for over a year. It is a fantastic series of lectures. One of the best things that has happened in education."
Prof. David Givol
Weizmann Institute, Israel

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