Henry Stewart Talks
The Biomedical & Life Sciences Collection
Online Seminars By Leading World Experts
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Biomedical & Life Sciences: All Series

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SERIES IN THIS COLLECTION

Published Series
Advances in Asthma
New mechanisms, management strategies and treatments
Advances in Chronic Obstructive Pulmonary Disease (COPD)
New mechanisms, management strategies and treatments
Agricultural Genetics
Understanding and improving plants and animals for food and agriculture
Alzheimer's Disease
Neurobiology, pathology and treatment
Antibiotic Resistance
From genes to global prevalence
Antivirals
Latest Developments and Future Progress
Apoptosis
Fundamentals, Pathways, Clinical Applications and Role in Disease
Autism and Autism Spectrum Disorders
History, Diagnosis, Neurobiology, Treatment and Outcome
Autoimmunity
Etiology, pathogenesis, clinical manifestation and diagnostic methodologies
Biology and Significance of Plasmids
A multi-talk discussion of extrachromosomal elements in microorganisms
Biomarkers
The path forward to highly sensitive and specific molecular diagnostics
The Blood-Brain Barrier
Understanding the regulatory gatekeeper between brain and body
Bone in Health and Disease
Bone Physiology and Osteoporosis
Calcium Signaling I
Regulation, Mechanisms, Effectors, Role in Disease and Recent Advances
Calcium Signaling II
Calcium and Disease
Cancer Pain Management
Advancing towards optimal symptom management
Cancer Therapy
Latest thinking in efficacy and toxicity
The Cell Division Cycle
Controlling when and where cells divide and differentiate
Cells of the Innate Immune System
Roles in health and disease
Cerebrovascular Disease
Diagnosis, Treatment and Prevention - a prioritized approach
Chemical Biology
The role of Chemistry in our fundamental understanding of Biology
Chloroplast
The Organelle that Sustains Us
Cognitive Neuroscience
Emergence of mind from brain
Copy Number Variation
Expanding the repertoire of genetic alterations in studies of natural variation and disease
Cytokines
Intercellular mediators regulating host defense
DNA Methylation
Physiology, pathology and disease
Drug Metabolizing Enzymes
Fundamentals, Study Methods, Recent Advances and Clinical Significance
The Endoplasmic Reticulum
Fundamentals and Role in Disease
Epigenetics
Concepts, Theories, Paradigms and Mechanisms
Epilepsy and Seizures
Causation, diagnosis and management
Eukaryotic Gene Regulation
From Chromatin to Transcription to mRNA Processing
Evolution and Medicine
How New Applications Advance Research and Practice
Free Radicals and the Oxygen Paradox
Oxidative Stress in Biology, Aging and Disease
From DNA to Proteins
The Multiple Levels of Regulation
Gastroenterology and Hepatology
Pathophysiology, presentation, diagnosis and management
Gene-Environment Interactions
Role in the Modulation of Pulmonary and Autoimmune Disease Risks
Genetic Epidemiology I
Fundamentals, Theory, Practice and Latest Developments
Genetic Epidemiology II
Latest Developments
Genetics of Cardiovascular Disease
Genetic interactions in a multifactorial disease
Glycobiology
The discovery of glycan function and its fundamental applications
Good Laboratory Practice
Principles, Compliance and Mutual Recognition
Human Population Genetics I
Evolution and Variation
Innate Immunity
Host recognition and response in health and disease
Introduction to Cheminformatics
Data management, manipulation and properties
Introduction to Human Genetics
Fundamentals and latest advances
Ion Channels
Mediators of ion currents across cell membranes
The Legacy of Drosophila Genetics
From 'defining the gene' to 'analyzing genome function'
Libraries in a Digital Age  Full series access
Fundamentals and latest thinking
Macrophage Heterogeneity and Function
Role in innate and adaptive immunity
The Mechanisms of Ribosome Function
Insights into protein synthesis
Medical Imaging
Imaging Techniques for Pre-clinical and Clinical Applications
Microarrays
Their design and use
Microbiota
Agents for Health and Disease
Mitochondrial Biogenesis
Processes, Regulation, Functions and Disease
Molecular Basis of Bacterial Infection
Virulence factors of pathogenic bacteria and how they work
Molecular Chaperones
Principles and Diseases
Monoclonal Antibodies as Therapeutic Agents
Fundamentals, Therapeutic Applications and Latest Advances
Natural Killer Cell Biology
Natural killer cell-mediated immunity to pathogens and cancer
Neurodegenerative Diseases
Fundamentals, Research Methods, Latest Advances
Neurotrauma
Basic research, clinical care and patients' perspectives
Non-Clinical Testing for Toxicity of Pharmaceuticals
Regulatory and Practical Standards for Testing and Application
Obesity
Epidemiology, Etiology, Consequences and Treatment
Pain and the Control of Pain
Pain transmission, regulation and management
Pharmaceutical Marketing
Latest insights, challenges, solutions and trends
Physiology and Pathophysiology of Neuroglia
Roles in health and disease
Prions and Amyloids
Self-propagating protein structures in mammals, yeast and fungi
Protein Epidemiology
Understanding Human Diseases at the Level of Protein Structure and Function
Protein Folding, Aggregation and Design
Concepts, Experiments, Theories and Mechanisms
Protein Homeostasis
Folding proteins and maintaining the protein-protein interaction networks
Protein Phosphorylation
A mechanism for regulating most aspects of cell life
Psychopharmacogenetics
Genetic Factors Influencing the Kinetics and Dynamics of Psychotropic Drugs
Retroviruses
Biology, Pathogenic Mechanisms and Treatment
RNA Interference
Principles and Applications
Signal Transduction via Protein Tyrosine Kinase Receptors
Structures, Function, Regulation, Mechanisms and Role in Disease
Stem Cells
Recent advances in understanding and utilizing
Stem Cells and Regenerative Medicine
Fundamentals, Therapeutic Applications and Ethical Considerations
Topical Talks
Talks of interest in the biomedical and life sciences
Vector-Borne Diseases
Characterization and epidemiology of arthropod transmitted infections
Viruses and Viral Diseases
Emerging threats to humans and animals
The World of Hormones
Molecular and Physiological Insights

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FREE TALK OF THE MONTH

Play 'AMPA-receptors and fast synaptic transmission in the brain'
AMPA-receptors and fast synaptic transmission in the brain More info
Prof. Stuart Cull-Candy

TOPICS COVERED IN THIS TALK

  • The fast component of excitatory synaptic transmission in the brain mediated by AMPARs
  • Functionally distinct AMPAR subtypes are involved in transmission (importance of topology)
  • How AMPAR diversity shapes transmission (implications of differential distribution and plasticity)
  • How AMPAR structure affects its behaviour and properties
  • Role of auxiliary AMPAR proteins (stargazin) in controlling AMPAR properties and diversity

POPULAR TALKS

Play 'Gene therapy and virotherapy in the treatment of cancer'
Gene therapy and virotherapy in the treatment of cancer More info
Prof. Leonard Seymour

TOPICS COVERED IN THIS TALK

  • Mutations and microenvironment in cancer
  • The challenge of cancer gene therapy
  • Cancer gene therapy strategies: p53 and TNF
  • Virotherapy against tumour cells
  • Virotherapy studies with wild-type vs. genetically-engineered viruses (Adenovirus, Vaccinia & Herpes)
  • Future of cancer virotherapy
Play 'Understanding poor Lymphatic function and how to improve it: Revisiting old facts and examining new leads to help wounds heal'
Understanding poor Lymphatic function and how to improve it: Revisiting old facts and examining new leads to help wounds heal More info
Prof. Neil Piller

TOPICS COVERED IN THIS TALK

  • Lymphoedema and oedema: key differences
  • Blood-tissue-lymph systems and their interfaces
  • Importance of the lymphatic system
  • Organization of superficial lymph system
  • Functioning of the lymphatic system
  • Consequences of poor lymph flow
  • Deep and superficial systems
  • The adipo-lymphatic connection
  • Fats in the diet: How they affect lymph flow and load
  • Lymphatic drainage from the small intestine
  • Blockage/overload and chylous reflux
  • Factors which determine lymph load and flow
  • Development of lymphoedema
  • Types of lymphoedemas
  • Increased subcutaneous fat reduces lymph transport
  • Build-up of fibrous tissues reduces lymphatic function
  • The problems of fibrosis
  • Proximity issues
  • Other limb swellings which look like lymphoedema which may underlie the wound area: Lipoedemas, Myxoedema and Phlebo-lymphoedema
  • Adipose tissue, fibrosis and lymphoedema
  • What can be done to improve tissue/cell health and improve wound healing?
Play 'The genetic basis of kidney cancer'
The genetic basis of kidney cancer More info
Dr. W. Marston Linehan

TOPICS COVERED IN THIS TALK

  • Renal Carcinoma
  • Stage I , Stage IV kidney cancer
  • Human Renal Epithelial Neoplasms
  • Loss of alleles in renal cell carcinoma
  • Mapping the Minimal 3p Loss Region in Clear Cell Renal Carcinoma
  • Studying Cancer Families to Identify Renal Carcinoma Genes
  • Identification of Kidney Cancer Genes
  • Inherited Forms of Renal Carcinoma
  • Clear Cell Renal Carcinoma: von Hippel Lindau (VHL)
  • VHL Gene
  • VHL Gene Localization Map
  • Germline VHL Mutations
  • Papillary Renal Carcinoma
  • Mouse Studies of VHL gene
  • VHL Gene Function
  • HIFα
  • Downstream effects of VHL mutation
  • Targeting VHL/HIF in Clear Cell RCC
  • TCGA Clear Cell Kidney Cancer
  • Intratumor Heterogeneity
  • Warburg effect in clear cell kidney cancer
  • Non-Clear Cell RCC
  • Locally Advanced Kidney Cancer
  • Hereditary Papillary Renal Carcinoma (HPRC)
  • Inherited Renal Carcinoma
  • Type 1 Papillary Renal Carcinoma
  • Penetrance of MET Mutation H1210R
  • MET Gene: Type 1 Papillary RCC
  • Location of the HPRC Gene
  • HPRC: Activating Mutations in the Tyrosine Kinase Domain of MET
  • Location of MET Mutations in the HPRC Patients
  • Targeting MET RCC Gene Pathway
  • Potential Small Molecule Target: MET Tyrosine Kinase Inhibition
  • Foretinib: Dual VEGFR and MET Inhibitor
  • MiT Kidney Cancer TFE3, TFEB, MITF
  • UOK124, Papillary Kidney Cancer
  • UOK124, UOK120, UOK 146 & TFE3 Kidney Cancer
  • Inherited Renal Carcinoma Birt-Hogg-Dubé (BHD)
  • Birt Hogg Dubé Cutaneous Manifestations
  • Kidney Tumors in BHD
  • BHD Renal Tumor Pathology
  • BHD Lung Cysts
  • Identification of the BHD Gene
  • Cutaneous Fibrofolliculomas
  • BHD Gene: Chromophobe RCC
  • BHD Gene Locus: Chromosome 17
  • BHD Protein Sequence
  • FLCN Mutation Spectrum
  • Therapeutic Approach: What Kind of Gene is FLCN?
  • BHD Gene Analysis in BHD-Associated RCC
  • Somatic mutations in renal tumors from BHD patients
  • UOK 257, BHD -/- RCC cell line Study
  • How Does the FLCN Gene Function?
  • Folliculin-FNIP1/2-AMPK Interactions
  • mTORC1/mTORC2 Activation: FLCN-Deficient Kidney Cancer
  • BHD Deletion Specifically in the Kidney
  • BHDf/d/KSPCre Mouse Kidney Study
  • Hereditary Leiomyomatosis Renal Cell Carcinoma (HLRCC)
  • HLRCC: Cutaneous Manifestations, Uterine Leiomyomas
  • HLRCC: Papillary Kidney Cancer Type 2
  • Orangophilic Nucleoli + Perinucleolar Halos
  • Fumarate Hydratase Gene: HLRCC
  • UOK-262 Study
  • Loss of a Krebs Cycle Enzyme Can Lead to Kidney Cancer
  • Impaired citric acid cycle and “Warburg effect”
  • HLRCC-Renal Cancer: Glucose-Dependent
  • PET Scan
  • HLRCC novel treatment approaches
  • Kidney Cancer: a Metabolic Disease

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