Q1. Randomization is a design technique:
A. to avoid blinding
B. to avoid bias
C. to support predictability
D. to avoid balance
E. to support enrollment
Q2. Which order of the randomization procedures results if you order from the lowest to the highest in terms of unpredictability?
A. Random Allocation Rule – Efrons Biased Coin Design - Complete Randomization
B. Complete Randomization – Big-Stick Design – Random Allocation Rule
C. Random Allocation Rule – Big-Stick Design – Complete Randomization
D. Big Stick Design – Efrons Biased Coin Design – Complete Randomization
E. Efrons Biased Coin Design – Complete Randomization – Random Allocation Rule
Q3. Which order of the randomization procedures results if you order from the highest to the lowest in terms of balancing?
A. Random Allocation Rule – Efrons Biased Coin Design – Big-Stick Design
D. Big Stick Design – Efrons Biased Coin Design – Random Allocation Rule
Q4. Which of the following metrics is NOT suitable for describing the potential contribution of bias to a test decision?
A. Loss in balancing
B. Proportion of sequences that meet the 5% significance level
C. Number of sequences exhibiting the nominal type-I-error probability
D. Number of correct guesses
E. Mean actual type-I-error probability
Q5. ERDO can be used to:
A. Identify the most appropriate trial design
B. Identify the effect size of the clinical scenario to justify sample size
C. Identify the most appropriate statistical model to mitigate bias on the study results
D. Identify an appropriate randomization procedure before the start of the study
E. Identify an appropriate blinding technique to mitigate bias on the study results