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- Design
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1. An introduction to randomization for clinical trials 1
- Prof. William Rosenberger
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2. An introduction to randomization for clinical trials 2
- Prof. William Rosenberger
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3. Randomisation, blinding and drug supply in interactive voice response trials
- Mr. Damian McEntegart
- Analysis
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4. Design and conduct of non-inferiority trials
- Prof. Valerie Durkalski-Mauldin
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5. Nonparametric covariate adjustment
- Prof. Michael Akritas
- Theory
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6. Historical and ethical issues in trial design
- Dr. J. Rosser Matthews
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7. Likelihood ratios and the strength of statistical evidence
- Prof. Jeffrey Blume
- Randomization, Masking and Allocation Concealment
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9. Detection of and adjustment for selection bias in randomized controlled clinical trials
- Prof. Lieven Nils Kennes
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10. Innovative and effective subject randomization methods
- Prof. Wenle Zhao
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11. Selection bias in studies with unequal allocation
- Dr. Olga M. Kuznetsova
- Archived Lectures *These may not cover the latest advances in the field
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12. Design and conduct of equivalence trials
- Prof. Valerie Durkalski-Mauldin
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13. Dose-finding trials in oncology
- Prof. Anastasia Ivanova
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14. Allocation concealment, prediction and selection bias
- Prof. David Torgerson
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15. Pseudo cluster randomization
- Dr. George Borm
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16. Introduction to flexible, adaptive trial design
- Dr. Cyrus Mehta
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17. Randomization in clinical trials
- Prof. William Rosenberger
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18. Novel methods for randomizing
- Dr. William Grant
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19. Permutation tests
- Dr. YanYan Zhou
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21. Multiple analyses in clinical trials
- Prof. Lemuel Moye
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22. Handling of missing data in clinical trials
- Dr. Linda Yau
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24. N-of-1 randomized clinical trials
- Prof. Patrick Onghena
Printable Handouts
Navigable Slide Index
- Introduction
- Outline
- Population model vs. invoked population model
- The randomization model
- The importance of randomization
- Outline - restricted randomization procedures
- Randomization sequence
- Restricted randomization
- Forced-balance procedures
- Permuted block design
- Adaptive restricted procedures
- Efron's biased coin design
- Wei's urn design (1)
- Wei's urn design (2)
- Outline - stratification
- Stratification (1)
- Stratification (2)
- Stratification (3)
- Outline - randomization as a basis for inference
- Randomization as a basis for inference
- Unconditional and conditional tests
- Family of linear rank tests (1)
- Family of linear rank tests (2)
- Family of linear rank tests (3)
- Using randomization tests
- Why not use them?
- The Lindeberg condition
- Large-sample test statistic
- Outline - other forms of randomization
- Other forms of randomization (1)
- Other forms of randomization (2)
Topics Covered
- Randomization model for clinical trials and comparison to traditional sampling-based models
- Examples of randomization procedures used in practice
- Exploration of randomization as a basis for inference under the framework of the family of linear rank tests
- Randomization for the practicing biostatistician
Links
Series:
Categories:
Talk Citation
Rosenberger, W. (2007, October 1). Randomization in clinical trials [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 20, 2024, from https://hstalks.com/bs/542/.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. William Rosenberger, Other: Lecture materials based on scholarly textbook published with John Wiley and Sons, accrues royalties.